Estrogen therapy selectively enhances prefrontal cognitive processes: a randomized, double-blind, placebo-controlled study with functional magnetic resonance imaging in perimenopausal and recently postmenopausal women.

Author: CohenLee S, GruberStaci, HallJanet E, JoffeHadine, MartinKathryn A, SarmientoIngrid A, Yurgelun-ToddDeborah

Paper Details 
Original Abstract of the Article :
Estrogen therapy (ET) seems to differentially effect cognitive processes in younger versus older postmenopausal women, suggesting a window of opportunity when ET is most beneficial. Cognitive improvement in younger postmenopausal women has been attributed to ET's influence on hot flushes and sleep, ...See full text at original site
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引用元:
https://doi.org/10.1097/01.gme.0000189618.48774.7b

データ提供:米国国立医学図書館(NLM)

Estrogen Therapy: A Cognitive Oasis in the Menopausal Desert

The world of [menopause] is a time of significant physiological change, and [estrogen therapy (ET)] is a common treatment option. This research investigates the [cognitive effects] of [ET] in [perimenopausal and recently postmenopausal women], using [functional magnetic resonance imaging (fMRI)] to examine brain activity.

Estrogen and the Brain: A Complex Relationship

The researchers found that [ET] selectively enhanced [prefrontal cognitive processes] in the study participants. This research suggests that estrogen may play a role in maintaining cognitive function during menopause. It's like discovering a hidden oasis of cognitive function in the desert of hormonal changes associated with menopause.

Navigating the Menopausal Transition

This research provides valuable insights into the potential cognitive benefits of [ET] for [women] during [menopause]. It underscores the importance of considering the impact of [hormonal changes] on brain function. The study reminds us that the journey through menopause is a complex one, and understanding the potential effects of hormonal fluctuations on cognitive health is crucial for navigating this transition.

Dr.Camel's Conclusion

The research on estrogen therapy and cognitive function during menopause suggests that ET may have a positive impact on prefrontal cognitive processes. The study highlights the complex relationship between hormones, brain function, and cognitive health during this transition. It encourages a thoughtful approach to understanding the potential benefits and risks of ET, recognizing that the menopausal desert can be navigated with careful consideration of individual needs and options.

Date :
  1. Date Completed 2006-08-02
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

16735938

DOI: Digital Object Identifier

10.1097/01.gme.0000189618.48774.7b

SNS
PICO Info
in preparation
Languages

English

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