Linear growth in prepubertal asthmatic children treated with montelukast, beclomethasone, or placebo: a 56-week randomized double-blind study.

Author: , BeckerAllan B, DassS Balachandra, KnorrBarbara A, KuznetsovaOlga, ReissTheodore F, Soto-QuirosManuel E, VermeulenJ, YoungBetty

Paper Details 
Original Abstract of the Article :
BACKGROUND: Antileukotrienes and inhaled corticosteroids are asthma controller agents widely used in the treatment of pediatric asthma. OBJECTIVE: To evaluate the effects of montelukast and beclomethasone on linear growth in prepubertal asthmatic children for 1 year. METHODS: This was a 30-center ...See full text at original site
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引用元:
https://doi.org/10.1016/s1081-1206(10)61342-7

データ提供:米国国立医学図書館(NLM)

Growth and Asthma Medications: A Long-Term Study in Children

The journey of growing up is a complex and delicate one, especially for children with asthma, a condition that can impact their physical development and overall well-being. This long-term study investigates the effects of montelukast and beclomethasone, two commonly used asthma medications, on linear growth in prepubertal children with mild persistent asthma. The researchers conducted a double-blind, double-dummy study over a year, measuring the impact of these medications on growth velocity.

Growth Rates and Asthma Medications: A Detailed Examination

The study revealed that montelukast did not significantly affect linear growth rates in prepubertal children with asthma. However, beclomethasone, a corticosteroid, resulted in a significant decrease in growth rate compared to placebo. This research is like a microscope, revealing the nuanced impact of these medications on the delicate process of childhood growth.

Balancing Asthma Control and Growth: A Careful Approach

This study, like a delicate dance between balancing two important factors, highlights the importance of carefully considering the potential effects of medications on growth when treating children with asthma. The findings suggest that montelukast may be a suitable alternative for children who require long-term asthma control without significant growth concerns. However, beclomethasone's impact on growth should be carefully monitored, and alternative strategies may need to be considered in certain cases. This research is a valuable guide, helping clinicians and parents navigate the complex world of asthma management in children.

Dr.Camel's Conclusion

This study, like a wise guide leading a group of young travelers through the desert of childhood asthma, investigates the potential impact of two commonly used asthma medications on linear growth. The findings suggest that montelukast may be a safe option for long-term asthma management, while beclomethasone's effect on growth should be carefully monitored. This research is a valuable resource for clinicians and parents alike, promoting informed decision-making in the care of children with asthma.

Date :
  1. Date Completed 2006-07-18
  2. Date Revised 2021-12-03
Further Info :

Pubmed ID

16802767

DOI: Digital Object Identifier

10.1016/s1081-1206(10)61342-7

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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