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The dose-response characteristics of inhaled corticosteroids when used to treat asthma: an overview of Cochrane systematic reviews.

Author: AdamsN P, JonesP W

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Inhaled corticosteroids are a cornerstone treatment for asthma. Different doses of beclometasone dipropionate, budesonide, and fluticasone propionate have different efficacy levels, with high doses of fluticasone having a higher risk of oral side effects.
Paper Details　
Original Abstract of the Article :
Inhaled corticosteroids form the cornerstone of treatment for most patients with asthma. A range of compounds are available with a wide range of prescribable doses. In this overview, we summarize the findings from a number of Cochrane systematic reviews that have examined the relative benefits of di...See full text at original site
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引用元：
https://doi.org/10.1016/j.rmed.2006.04.015

データ提供：米国国立医学図書館（NLM）

Dose-Response of Inhaled Corticosteroids in Asthma Treatment

Asthma, a chronic respiratory condition, often requires ongoing medication management. This research explores the dose-response characteristics of inhaled corticosteroids (ICS), a cornerstone of asthma treatment. The authors summarize findings from several Cochrane systematic reviews that examined the efficacy of different doses of beclometasone dipropionate, budesonide, and fluticasone propionate in children and adults with asthma. This study provides valuable information for healthcare professionals regarding the appropriate dosage and potential risks associated with ICS use.

Dose-Response Relationship Exists for Inhaled Corticosteroids

The study highlights the existence of a dose-response relationship for ICS efficacy. However, it emphasizes that most of the benefit in mild-to-moderate asthma is achieved with low-to-moderate doses. Higher doses, while offering marginal improvement, may increase the risk of oral side effects. This information underscores the importance of individualized dosage adjustments based on patient needs and response to treatment.

Optimizing Asthma Treatment with Inhaled Corticosteroids

This research contributes to our understanding of ICS use in asthma management. By understanding the dose-response relationship and potential side effects, healthcare professionals can tailor treatment regimens to individual patients, maximizing benefits and minimizing risks. This study emphasizes the importance of ongoing monitoring and adjustment of ICS doses based on patient response and clinical needs.

Dr.Camel's Conclusion

Imagine a camel navigating a dusty desert, seeking the perfect balance of water and shade. This research is like a map, guiding us through the complexities of ICS use in asthma management. It emphasizes the importance of finding the right dose, like finding the perfect oasis, to effectively manage the condition while minimizing side effects. This study underscores the need for careful consideration and ongoing adjustments in asthma treatment to achieve the best possible outcomes for patients.

Date :
  1. Date Completed 2007-03-23
  2. Date Revised 2022-03-30
Further Info :

Pubmed ID

16806876

DOI: Digital Object Identifier

10.1016/j.rmed.2006.04.015

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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