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Effectiveness of intranasal zolmitriptan in acute cluster headache: a randomized, placebo-controlled, double-blind crossover study.

Author: BussoneGennaro, CittadiniElizabeth, EversStefan, GoadsbyPeter J, MayArne, StraubeAndreas

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Five-milligram and 10-mg doses of zolmitriptan intranasal spray are effective within 30 minutes and well tolerated in the treatment of acute cluster headache.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Cluster headache is a form of primary headache in which attacks are rapid in onset with very severe pain. The mainstays of acute therapy are inhaled oxygen and sumatriptan succinate injection. OBJECTIVE: To evaluate zolmitriptan nasal spray in the acute treatment of cluster headache. M...See full text at original site
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引用元：
https://doi.org/10.1001/archneur.63.11.nct60002

データ提供：米国国立医学図書館（NLM）

Cluster Headache: A Camel's Journey Through Pain Relief

Cluster headaches are a debilitating form of headache characterized by intense, recurring pain. This study investigates the effectiveness of intranasal zolmitriptan in treating acute cluster headaches. The researchers conducted a randomized, placebo-controlled, double-blind crossover study to compare the effectiveness of different doses of zolmitriptan nasal spray to placebo.

A Camel's Relief: Finding Hope for Headache Sufferers

This study offers hope for individuals suffering from cluster headaches. The researchers found that intranasal zolmitriptan, particularly at a 10mg dose, was significantly more effective than placebo in providing headache relief within 30 minutes.

The Camel's Wisdom on Headache Treatment: Exploring New Options

This study highlights the importance of exploring new treatment options for cluster headaches. It demonstrates the effectiveness of intranasal zolmitriptan as a potential alternative or adjunct to other treatments.

Dr. Camel's Conclusion

Just as a camel seeks shade from the scorching desert sun, finding relief from cluster headaches can be a challenging journey. This study offers a beacon of hope for headache sufferers, highlighting the potential of intranasal zolmitriptan as an effective treatment option.

Date :
  1. Date Completed 2006-12-12
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

16966497

DOI: Digital Object Identifier

10.1001/archneur.63.11.nct60002

Related Literature

Article Analysis
・Effects of zolmitriptan nasal spray
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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