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Electrophysiological effects of brompheniramine on cardiac ion channels and action potential.
Author: KimEun-Joo, KimKi-Suk, ShinWon-Ho
Original Abstract of the Article :
Some antihistamines (mainly terfenadine and astemizole) have been demonstrated to cause QT interval prolongation and, in some cases, torsade-de-pointes. We investigated the cardiac electrophysiological effects of brompheniramine, a conventional antihistamine. Brompheniramine was reported to prolong ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.phrs.2006.08.004
データ提供:米国国立医学図書館(NLM)
Electrophysiological Effects of Brompheniramine on Cardiac Ion Channels: A Camel's Perspective
The field of [cardiology] is always seeking to understand the effects of medications on our hearts. This research investigates the [electrophysiological] effects of [brompheniramine], a common [antihistamine], on [cardiac ion channels] and [action potential]. The authors used a combination of [whole-cell patch clamp techniques] and [conventional microelectrode recording techniques] to examine the impact of [brompheniramine] on different heart cells, finding that it can affect various [ion channels] and potentially alter [action potential] duration. This study emphasizes the importance of considering the potential cardiovascular effects of even seemingly safe medications.
Navigating the Complex Landscape of Cardiac Electrophysiology
This study dives into the complex world of [cardiac electrophysiology], investigating the impact of a common [antihistamine] on the heart's electrical activity. The researchers found that [brompheniramine] can have significant effects on [cardiac ion channels], potentially affecting [action potential] duration. This highlights the importance of considering the potential cardiovascular effects of even seemingly safe medications.
Camel's Thoughts on Cardiac Ion Channels
Just as a camel needs to be mindful of the terrain it traverses, individuals need to be aware of the potential impact of medications on their hearts. This study emphasizes the importance of consulting with a healthcare professional to understand the potential risks and benefits of any medication, particularly those that might affect the delicate balance of our cardiovascular system.
Dr. Camel's Conclusion
This research underscores the importance of understanding the intricate workings of our hearts and the potential effects of medications on these delicate systems. The study's findings serve as a reminder to approach medication use with caution and to always seek guidance from healthcare professionals. Like a camel carefully choosing its path through the desert, we should be mindful of the potential pitfalls when it comes to our health, particularly when considering the impact of medications on our hearts.
Date :
- Date Completed 2007-01-23
- Date Revised 2015-08-31
Further Info :
Related Literature
English
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