Paper Details 
Original Abstract of the Article :
AIM: Achievement of target blood pressure (BP) levels in subjects with metabolic syndrome (MS) by the method of stepwise antihypertensive therapy and assessment of metabolic effects of combination of spirapril and nifedipine retard. MATERIAL AND METHODS: Patients (n=20, 12 women, 8 men, mean age 54...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/17047619

データ提供:米国国立医学図書館(NLM)

A Rational Approach to Antihypertensive Therapy in Patients with Metabolic Syndrome

Metabolic syndrome is a cluster of risk factors that increases the likelihood of developing heart disease, stroke, and type 2 diabetes. It's like a desert ecosystem where various factors are interconnected, contributing to a delicate balance that can easily be disrupted. This study investigates the effectiveness of spirapril, an ACE inhibitor, and its combination with nifedipine retard, a calcium channel blocker, in managing hypertension in patients with metabolic syndrome. The researchers aimed to determine the optimal antihypertensive regimen for this patient population.

Spirapril and Nifedipine Retard: A Potential Solution for Hypertension in Metabolic Syndrome

The study found that both spirapril monotherapy and combination therapy with nifedipine retard were effective in lowering blood pressure in patients with metabolic syndrome. Furthermore, the combination therapy demonstrated positive metabolic effects, including a decrease in triglyceride levels and an increase in high-density lipoprotein cholesterol levels. These findings suggest that spirapril and nifedipine retard may be valuable tools for managing hypertension and improving metabolic health in this patient population.

Navigating the Desert of Metabolic Syndrome

This study highlights the importance of a comprehensive approach to managing metabolic syndrome. It emphasizes the need to address hypertension effectively, as well as to consider the potential metabolic benefits of certain medications. It's like navigating a desert landscape, where a multi-pronged approach is crucial for success. By taking a holistic view of patient health and considering the interplay of different risk factors, healthcare professionals can better manage metabolic syndrome and prevent its devastating complications.

Dr.Camel's Conclusion

This study demonstrates that spirapril and nifedipine retard can be effective in managing hypertension in patients with metabolic syndrome. It's like providing a reliable source of water and shade in a harsh desert environment. By addressing the underlying metabolic factors that contribute to hypertension, we can improve the overall health and well-being of patients with this condition.

Date :
  1. Date Completed 2006-10-31
  2. Date Revised 2017-11-16
Further Info :

Pubmed ID

17047619

DOI: Digital Object Identifier

17047619

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