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Intrathecal topotecan in adult patients with neoplastic meningitis.

Author: BenvenutiMatthew, BhattMansi S, GammonDavid C, GlantzMichael J, TranLan, Van HornAlexis

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Intrathecal topotecan appeared to be effective and safe in adult patients with neoplastic meningitis (NM).
Paper Details　
Original Abstract of the Article :
PURPOSE: The efficacy and safety of intrathecal topotecan were assessed in patients with neoplastic meningitis (NM) by retrospective chart review. SUMMARY: Fourteen patients (median age, 57 years) with NM were treated with the standard of care (i.e., regional or systemic chemotherapy or irradiation...See full text at original site
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引用元：
https://doi.org/10.2146/ajhp060165

データ提供：米国国立医学図書館（NLM）

Intrathecal Topotecan: A New Oasis for Neoplastic Meningitis

[Neoplastic meningitis (NM)] is a serious condition affecting the central nervous system. This study, like a camel navigating a challenging desert landscape, investigates the effectiveness of [intrathecal topotecan] in treating NM. The researchers found that intrathecal topotecan was effective and well-tolerated in patients with NM, leading to a significant reduction in malignant cells in the cerebrospinal fluid (CSF) in a majority of patients. These findings offer a glimmer of hope for patients battling this challenging disease.

A Ray of Hope for Neoplastic Meningitis: A Promising Treatment

The study's findings suggest that intrathecal topotecan holds promise for the treatment of NM. This is significant news as it offers hope for improved outcomes for patients battling this disease.

Navigating the Desert of Disease: A Reminder

The desert of disease can be vast and unforgiving, but there are always oases of hope. If you or someone you know is facing a health challenge, seek professional medical advice and stay optimistic. Remember, medical research continues to advance, offering new treatments and breakthroughs every day.

Dr.Camel's Conclusion

This research, like a guiding star in the desert, provides valuable insights into the potential of intrathecal topotecan for treating NM. The study's findings offer hope for a future where patients with NM can experience improved outcomes and live longer, healthier lives.

Date :
  1. Date Completed 2007-01-30
  2. Date Revised 2019-01-01
Further Info :

Pubmed ID

17057045

DOI: Digital Object Identifier

10.2146/ajhp060165

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Article Analysis
・Side Effects of topotecan injection
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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