Paper Details 
Original Abstract of the Article :
The inhibitory effects of ticlopidine on platelet function were evaluated in 18 healthy male volunteers using three different platelet function tests. Three methods include the recently developed small collagen-beads method, which evaluates the platelet response in whole blood samples under shear st...See full text at original site
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引用元:
https://doi.org/10.1016/j.ejps.2006.09.003

データ提供:米国国立医学図書館(NLM)

Measuring the Impact of Ticlopidine on Platelet Function

In the vast landscape of medicine, platelet function plays a crucial role in maintaining the delicate balance of blood clotting. Ticlopidine, an antiplatelet drug, is commonly used to prevent blood clots, but its effects on platelet function can vary depending on the method of measurement. This study investigates the inhibitory effects of ticlopidine on platelet function using three different methods, aiming to determine the most accurate and reliable approach.

Comparing Platelet Function Tests: A Quest for Accuracy

The study compared the results of three platelet function tests: the small collagen-beads method, conventional platelet aggregometry, and a cone-plate viscometer. While all three methods revealed ticlopidine's inhibitory effects on platelet function, the study found that the collagen-beads method was particularly effective at detecting ticlopidine's impact on platelet retention rates, especially at higher retention rates. This method's use of whole blood samples under shear stress conditions adds to its practicality. The findings highlight the importance of choosing the appropriate platelet function test to accurately assess the effects of antiplatelet drugs.

Optimizing Antiplatelet Therapy for Patient Safety

This study serves as a reminder that the choice of platelet function test can significantly impact the interpretation of antiplatelet drug effects. The study's findings underscore the importance of using a test that is both accurate and reliable to monitor the effects of ticlopidine therapy, ensuring optimal patient safety and minimizing potential risks. As we continue to explore the intricate world of platelet function, we must remain diligent in our quest for the most effective and safe methods for monitoring antiplatelet therapy.

Dr. Camel's Conclusion

Platelet function is a delicate dance, and understanding its nuances is crucial in managing blood clotting disorders. This study, like a skilled camel trainer, guides us towards the most accurate and reliable methods for measuring platelet function. The findings highlight the importance of precision in our assessments, ensuring that we can navigate the complexities of platelet function with confidence and provide the best possible care for our patients. As we continue to explore the mysteries of blood clotting, we must embrace the pursuit of knowledge and strive for excellence in our clinical practice.

Date :
  1. Date Completed 2007-02-23
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

17070023

DOI: Digital Object Identifier

10.1016/j.ejps.2006.09.003

Related Literature

SNS
PICO Info
in preparation
Languages

English

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