Efficacy and side-effects of prazosin as a symptomatic treatment of benign prostatic obstruction.

Author: HanssonE, JuuselaH E, MattilaM J, PermiJ E, RuskJ I, RuutuM L, SotarautaM T, TaljaM T, WuokkoE J

Paper Details 
Original Abstract of the Article :
This randomized double-blind crossover trial was conducted to assess the effects of prazosin, an alpha 1-adrenoceptor blocking drug, on the voiding of 35 patients with benign prostatic obstruction. Maximum and mean flow rates, residual urine, blood pressure and heart rate were measured at baseline a...See full text at original site
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引用元:
https://doi.org/10.3109/00365599109024522

データ提供:米国国立医学図書館(NLM)

Efficacy and Side-Effects of Prazosin as a Symptomatic Treatment of Benign Prostatic Obstruction

The authors investigate the effectiveness of [prazosin], an alpha 1-adrenoceptor blocking drug, in treating [benign prostatic obstruction (BPO)]. The study employed [a randomized double-blind crossover trial] to assess the impact of prazosin on [voiding parameters] in patients with BPO. The key finding is that [prazosin significantly improved voiding parameters in patients with BPO].

Prazosin Offers a Viable Treatment Option for BPO

The study demonstrates that [prazosin can be a valuable treatment option for BPO], providing relief from symptoms such as [difficulty urinating]. The findings revealed that [maximum and mean flow rates increased significantly during prazosin treatment, as also did the maximum and mean voided volumes]. While [subjective improvements in voiding were not statistically significant], the objective improvements in flow rates suggest that [prazosin may be an effective alternative for patients seeking symptomatic relief from BPO].

Understanding the Potential Side Effects of Prazosin

While [prazosin appears to offer benefits for BPO], it's important to be aware of the potential side effects. The study found that [prazosin caused postural dizziness more often than placebo]. Patients should [discuss any potential side effects with their doctor] to ensure safe and effective management of BPO.

Dr.Camel's Conclusion

This research shows that prazosin can be a helpful tool for men facing the challenges of BPO. Like a camel navigating a sandstorm, finding the right treatment for BPO can be a challenge. This study provides valuable insights into the potential of prazosin as a safe and effective treatment for BPO.

Date :
  1. Date Completed 1991-07-16
  2. Date Revised 2019-09-02
Further Info :

Pubmed ID

1710823

DOI: Digital Object Identifier

10.3109/00365599109024522

Related Literature

SNS
PICO Info
in preparation
Languages

English

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