Testosterone inhibits estrogen/progestogen-induced breast cell proliferation in postmenopausal women.

Author: HirschbergAngelica Lindén, HoflingMarie, HägerströmTorsten, SkoogLambert, TaniEdneia, von SchoultzBo

Paper Details 
Original Abstract of the Article :
During the past few years serious concern has been raised about the safety of combined estrogen/progestogen hormone therapy, in particular about its effects on the breast. Several observations suggest that androgens may counteract the proliferative effects of estrogen and progestogen in the mammary ...See full text at original site
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引用元:
https://doi.org/10.1097/01.gme.0000232033.92411.51

データ提供:米国国立医学図書館(NLM)

Exploring the Impact of Testosterone on Breast Cell Proliferation in Postmenopausal Women

In the field of [women's health], the [safety and efficacy] of [hormone therapy] is a topic of ongoing research and debate. This study investigated the [effects of testosterone addition] on [breast cell proliferation] during [postmenopausal estrogen/progestogen therapy]. The researchers found that [testosterone can inhibit estrogen/progestogen-induced breast cell proliferation], suggesting a potential protective effect against [estrogen-related breast cancer risk]. These findings contribute to the understanding of the complex interplay between [hormones] and [breast tissue health] in postmenopausal women.

The Protective Role of Testosterone in Postmenopausal Breast Health

This study provides compelling evidence that [testosterone] may play a significant role in [mitigating the proliferative effects of estrogen and progestogen] in the breast. The researchers' findings suggest that [testosterone] could be a valuable component of [hormone therapy regimens] for postmenopausal women, potentially reducing the risk of [estrogen-related breast cancer].

Hormone Therapy and Breast Health: Understanding the Complexities

The research on [testosterone's influence on breast cell proliferation] underscores the importance of a comprehensive understanding of the [complex interplay between hormones] in postmenopausal women. It highlights the potential of [hormone therapy] to provide both [benefits and risks] and emphasizes the need for individualized care based on individual risk factors and health goals.

Dr.Camel's Conclusion

Imagine a delicate balance of sand, wind, and water shaping the ever-changing landscape of a desert dune. Similarly, the balance of hormones plays a crucial role in the health and well-being of postmenopausal women. This study, like a skillful sculptor shaping a delicate dune, reveals the complex interplay between testosterone and other hormones in the breast. The findings suggest that testosterone may offer a protective effect against estrogen-related risks, highlighting the importance of a holistic approach to hormone therapy and maintaining breast health.
Date :
  1. Date Completed 2007-06-21
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

17108847

DOI: Digital Object Identifier

10.1097/01.gme.0000232033.92411.51

SNS
PICO Info
in preparation
Languages

English

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