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Daily dose of interferon alpha-2b and ribavirin in treatment-naive patients with chronic hepatitis C virus genotype 1 infection: a randomised controlled study.
Author: , BalzolaFederico, BellatiGiorgio, BenettiGianpiero, BorzioMauro, ColomboAlberto, CroceGuido, FargionSilvia, IamolettiCarlo, RamellaGiuliano, RizzettoMario
Original Abstract of the Article :
OBJECTIVE: The treatment of patients with hepatitis C virus (HCV) genotype 1 infection remains disappointing. METHODS: In 1999, we started a multicentre study comparing two regimens of recombinant interferon (IFN) alpha-2b plus ribavirin. Group A (90 patients) received ribavirin plus IFN alpha-2b 5...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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引用元:
https://doi.org/10.1007/BF02936535
データ提供:米国国立医学図書館(NLM)
A Study of Interferon Alpha-2b and Ribavirin for Hepatitis C Genotype 1
The treatment of hepatitis C virus (HCV) genotype 1 infection is a challenging journey through the desert of medical research. This study explored the effectiveness of two different treatment regimens involving interferon alpha-2b and ribavirin, both commonly used antiviral drugs, in patients with HCV genotype 1 infection. The researchers conducted a randomized controlled trial, where patients were randomly assigned to receive one of the two treatment regimens.
Examining Treatment Regimens and Outcomes
The researchers compared the effectiveness of a regimen that included a 4-week induction therapy with a standard regimen that did not. The study found that while both regimens were well-tolerated, the induction therapy regimen showed a slight advantage in terms of achieving sustained virological response (SVR), which means the virus was successfully eliminated.
A Glimpse of Hope for Treatment-Naive Patients
The study provides a glimmer of hope for treatment-naive patients with HCV genotype 1 infection. The results suggest that a 4-week induction therapy regimen may be a more effective treatment option compared to the standard regimen. It's like discovering a hidden oasis, offering a better chance of survival in the desert of HCV infection.
Dr. Camel's Conclusion
The study offers valuable insights into the treatment of HCV genotype 1 infection, reminding us that the search for better treatments is an ongoing journey. While the results are promising, further research is needed to solidify these findings and explore the long-term effects of these treatment regimens. We must continue our exploration of this complex disease, seeking new pathways and innovative solutions to improve the lives of those affected by HCV.
Date :
- Date Completed 2007-01-04
- Date Revised 2019-11-10
Further Info :
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