Effectiveness of switching from adjuvant tamoxifen to anastrozole in postmenopausal women with hormone-sensitive early-stage breast cancer: a meta-analysis.

Author: BoccardoFrancesco, GnantMichael, GreenwoodMike, JakeszRaimund, JonatWalter, KaufmannManfred, RubagottiAlessandra, ZunaIvan

Paper Details 
Original Abstract of the Article :
For more than 20 years, tamoxifen has been the mainstay of adjuvant endocrine therapy for women with hormone-sensitive early-stage breast cancer. However, not only does tamoxifen have potential side-effects such as an increased risk of endometrial cancer and thromboembolic events, but patients can a...See full text at original site
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引用元:
https://doi.org/10.1016/S1470-2045(06)70948-2

データ提供:米国国立医学図書館(NLM)

Switching Endocrine Therapies: Finding New Oasis in Breast Cancer Treatment

This research explores the effectiveness of switching from tamoxifen to anastrozole for treating postmenopausal women with hormone-sensitive early-stage breast cancer. Tamoxifen, a mainstay treatment for decades, has shown effectiveness but can also have side effects. Researchers, like seasoned explorers seeking a better route through the desert of cancer treatment, investigated the potential benefits of switching to anastrozole, a newer aromatase inhibitor.

A New Path Through the Dunes of Breast Cancer

The researchers conducted a meta-analysis, combining results from multiple studies to determine the overall effectiveness of switching therapies. Their findings suggest that switching from tamoxifen to anastrozole after 2-3 years may be more effective than continuing tamoxifen for a total of 5 years. This is an encouraging discovery, providing a potential pathway for improved outcomes for breast cancer patients.

Navigating the Oasis of Breast Cancer Treatment

This research sheds light on the importance of exploring new treatment options for breast cancer, just as a camel seeks a more efficient route through the desert. The findings suggest that switching therapies could offer potential benefits for patients, potentially improving treatment outcomes while minimizing side effects.

Dr.Camel's Conclusion

This study provides a fresh perspective on breast cancer treatment, revealing the potential benefits of switching therapies. It's like discovering a new oasis in the vast desert of cancer treatment, offering a more effective and personalized approach to care.

Date :
  1. Date Completed 2007-03-27
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

17138220

DOI: Digital Object Identifier

10.1016/S1470-2045(06)70948-2

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English

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