Topical dorzolamide 2%/timolol 0.5% ophthalmic solution: a review of its use in the treatment of glaucoma and ocular hypertension.

Author: FramptonJames E, PerryCaroline M

Paper Details 
Original Abstract of the Article :
Topically administered dorzolamide 2%/timolol 0.5% (dorzolamide/timolol ophthalmic solution; Cosopt) is a fixed combination of two ocular hypotensive drugs (the carbonic anhydrase inhibitor dorzolamide and the beta-adrenoceptor antagonist timolol) that have an additive effect on lowering intraocular...See full text at original site
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引用元:
https://doi.org/10.2165/00002512-200623120-00005

データ提供:米国国立医学図書館(NLM)

Topical Dorzolamide/Timolol: A Powerful Duo for Glaucoma

This study focuses on the use of a fixed combination of dorzolamide and timolol, two medications commonly used to treat glaucoma and ocular hypertension. Glaucoma, a serious eye condition, is characterized by increased pressure within the eye, which can lead to damage to the optic nerve and vision loss. The study explores the effectiveness and safety of this fixed combination in managing this condition.

A Combined Approach: Synergy for Lowering IOP

The study highlights the synergistic effect of dorzolamide and timolol in lowering intraocular pressure (IOP), the primary target in glaucoma management. The combination provides a more effective treatment option compared to using either drug alone. This approach is like combining two different types of sand to create a more stable dune - the combined forces of dorzolamide and timolol create a more powerful and lasting effect on IOP.

Convenience and Safety: A Well-Tolerated Solution

Beyond its effectiveness, the study emphasizes the convenience and safety of the fixed combination. The fixed combination offers a single-drop formulation, simplifying the treatment regimen for patients. Furthermore, the combination has been shown to be generally well tolerated, with minimal side effects. This is a significant advantage for patients who may experience discomfort or inconvenience with multiple medications.

Dr. Camel's Conclusion

This research provides valuable insights into the use of a fixed combination of dorzolamide and timolol for glaucoma management. This powerful duo offers a convenient, effective, and well-tolerated treatment option for patients, helping them navigate the desert of glaucoma with greater ease and comfort.

Date :
  1. Date Completed 2007-05-01
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

17154662

DOI: Digital Object Identifier

10.2165/00002512-200623120-00005

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SNS
PICO Info
in preparation
Languages

English

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