Paper Details

  1. Home
  2. Paper Details

Delaying the primary surgical effort for advanced ovarian cancer: a systematic review of neoadjuvant chemotherapy and interval cytoreduction.

Author: BristowRobert E, ChiDennis S, EisenhauerEric L, SantillanAntonio

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Interval cytoreductive surgery following a concerted but suboptimal attempt at up-front cytoreduction does not appear to have an appreciable impact on survival outcome in patients with advanced-stage ovarian cancer. Neoadjuvant chemotherapy represents a viable alternative management strategy for patients felt to be optimally unresectable; however, currently available data suggest that the survival outcome achievable with initial chemotherapy is inferior to successful up-front cytoreductive surgery.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To summarize the existing data on interval cytoreductive surgery and neoadjuvant chemotherapy as alternative treatment strategies for patients with advanced-stage ovarian cancer. METHODS: All investigational studies with evaluable survival data on interval cytoreductive surgery and neoad...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.ygyno.2006.11.002

データ提供：米国国立医学図書館（NLM）

Navigating the Desert of Ovarian Cancer: A Tale of Two Strategies

Ovarian cancer, a stealthy foe, often hides in the shadows, like a mirage in the desert, making early detection a difficult task. When diagnosed in advanced stages, the journey to recovery can be long and arduous, demanding a strategic approach to maximize chances of survival.

This study investigates two alternative treatment strategies for advanced-stage ovarian cancer: interval cytoreductive surgery and neoadjuvant chemotherapy. The researchers, like skilled desert navigators, analyze the available evidence to compare these two approaches. Their findings suggest that maximal primary cytoreductive surgery remains the gold standard for the majority of patients, while neoadjuvant chemotherapy may be a viable option for a select group of patients deemed unresectable by surgery.

The Oasis of Survival: Choosing the Right Path

The study's findings highlight the importance of individualized treatment plans for ovarian cancer patients. Just as a desert traveler chooses the most appropriate route based on the terrain, clinicians must carefully assess each patient's condition and select the treatment strategy that offers the best chance of survival. This is like finding a hidden oasis in the desert, offering a lifeline of hope and a pathway to recovery.

A Desert of Uncertainty

While the study provides valuable insights, it also underscores the need for further research to develop universal selection criteria for neoadjuvant chemotherapy and optimize treatment strategies. The journey to conquering ovarian cancer, like a desert trek, is an ongoing one, requiring continuous exploration and innovation to find the most effective solutions.

Dr. Camel's Conclusion

This review provides a valuable roadmap for navigating the complex desert landscape of advanced ovarian cancer. By understanding the benefits and limitations of different treatment strategies, we can empower clinicians to provide personalized care and offer patients the best chance of survival.

Date :
  1. Date Completed 2007-03-20
  2. Date Revised 2022-03-09
Further Info :

Pubmed ID

17166564

DOI: Digital Object Identifier

10.1016/j.ygyno.2006.11.002

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.