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Gabapentin's acute effect on mood profile -- a controlled study on patients with alcohol withdrawal.

Author: BangerMarkus, BonnetUdo, LewekeF Markus, NyhuisPeter, SpeckaMichael

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Gabapentin selectively accelerated the improvement of the vigor-subscore of patients with acute alcohol withdrawal within 48 hours. This effect was independent from the subjective severity of withdrawal and especially marked in patients with co-morbid mild depression.
Paper Details　
Original Abstract of the Article :
RATIONALE: Delayed beneficial effects of gabapentin on mood were frequently reported in various patient populations. This is the first controlled study which addressed acute effects of gabapentin on mood. METHODS: Analysis of the German version of Profile of Mood States (POMS) throughout a randomis...See full text at original site
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引用元：
https://doi.org/10.1016/j.pnpbp.2006.11.006

データ提供：米国国立医学図書館（NLM）

Gabapentin's Impact on Mood: A Journey Through the Desert of Alcohol Withdrawal

Alcohol withdrawal is a challenging condition, often accompanied by mood changes and emotional distress. This study ventures into the desert of alcohol withdrawal, examining the acute effects of gabapentin on mood. The researchers conducted a randomized, placebo-controlled, double-blinded study, finding that gabapentin selectively accelerated the improvement of the vigor-subscore in patients with acute alcohol withdrawal. This effect was particularly pronounced in patients with co-morbid mild depression.

Gabapentin: A Potential Oasis in the Desert of Alcohol Withdrawal

The study suggests that gabapentin might offer potential benefits for mood management during alcohol withdrawal. This research provides valuable insights into the effects of gabapentin on mood and suggests its potential role in managing alcohol withdrawal symptoms.

Navigating the Desert of Alcohol Withdrawal: A Compass for Recovery

The study emphasizes the importance of understanding the mood changes associated with alcohol withdrawal and highlights the potential of gabapentin in managing these symptoms. This research provides valuable information for healthcare providers and individuals seeking to navigate the challenges of alcohol withdrawal.

Dr. Camel's Conclusion

This study examines the acute effects of gabapentin on mood in patients with alcohol withdrawal. The research suggests that gabapentin may have potential benefits for mood management during alcohol withdrawal, particularly for individuals with co-morbid mild depression.

Date :
  1. Date Completed 2007-04-24
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

17178181

DOI: Digital Object Identifier

10.1016/j.pnpbp.2006.11.006

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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