Sustained remission and reduced radiographic progression with combination disease modifying antirheumatic drugs in early rheumatoid arthritis.

Author: BlåfieldHarri, HakolaMikko, HannonenPekka, KautiainenHannu, KorpelaMarkku, LaasonenLeena, Leirisalo-RepoMarjatta, MäkinenHeidi, MöttönenTimo, SokkaTuulikki

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To study sustainability of remission and good treatment response, and the association of both with radiographic progression, in early rheumatoid arthritis (RA) in the Finnish Rheumatoid Arthritis Combination Therapy trial (FIN-RACo). METHODS: Patients were randomized to receive either a ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/17183623

データ提供:米国国立医学図書館(NLM)

Combination Therapy for Early Rheumatoid Arthritis: A Path to Remission

Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes pain, stiffness, and inflammation in the joints. This study examined the effectiveness of combination therapy, using multiple disease-modifying antirheumatic drugs (DMARDs), in treating early RA compared to single-DMARD therapy.

Sustained Remission and Reduced Radiographic Progression

The study found that combination therapy led to a greater proportion of patients achieving remission at two years and sustained remission at 6, 12, and 24 months. Furthermore, patients who achieved sustained remission experienced less radiographic joint damage than those who did not. This suggests that combination therapy may help to slow the progression of RA.

Implications for Early RA Management

These findings, like a compass guiding us towards effective treatment strategies for RA, suggest that combination therapy may offer a promising approach to managing the disease in its early stages. Early intervention with combination therapy may help to improve outcomes and reduce the long-term consequences of RA.

Dr.Camel's Conclusion

This research, like a desert oasis offering respite from the scorching heat of RA, provides valuable insights into the potential benefits of combination therapy for patients with early RA. By combining multiple DMARDs, we may be able to achieve more sustained remission and slow the progression of this debilitating disease.

Date :
  1. Date Completed 2007-07-09
  2. Date Revised 2022-04-09
Further Info :

Pubmed ID

17183623

DOI: Digital Object Identifier

06/13/1211

Related Literature

SNS
PICO Info
in preparation
Languages

English

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