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Treatment of streptococcal endocarditis with a single daily dose of ceftriaxone sodium for 4 weeks. Efficacy and outpatient treatment feasibility.

Author: EtienneJ, FrancioliP, GerberA, HoignéR, ThysJ P

Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
CommentA short article/note that provides an opinion/perspective/interpretation on a published paper/topic.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Ceftriaxone sodium was found to be effective and safe in the treatment of streptococcal endocarditis. In a study of 59 patients, no patients experienced a relapse after 4 months to 5 years of follow-up. Treatment was uneventful in 71% of patients, and the most common side effect was drug allergy.
Paper Details　
Original Abstract of the Article :
OBJECTIVE--To evaluate the efficacy and safety of ceftriaxone sodium in the treatment of streptococcal endocarditis. DESIGN--An open, multicenter, noncomparative study with a follow-up of patients for 4 months to 5 years. SETTING--Internal medicine wards and outpatient clinics of hospitals of variou...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/1727524

データ提供：米国国立医学図書館（NLM）

A New Era for Treating Streptococcal Endocarditis

Infectious diseases pose a significant threat to human health, and endocarditis, an infection of the heart's inner lining, can be a particularly challenging condition. This study explores the effectiveness and feasibility of using a single daily dose of ceftriaxone sodium for 4 weeks in the treatment of streptococcal endocarditis. The researchers conducted a multicenter, noncomparative study to evaluate the efficacy and safety of this treatment regimen.

Ceftriaxone Sodium: A Promising Treatment

The study found that ceftriaxone sodium administered as a single daily dose for 4 weeks was effective in treating streptococcal endocarditis, with no relapses observed in the patients who completed the treatment. The treatment was generally well-tolerated, with few adverse effects. The researchers highlight the ease of administration of this regimen, noting that a significant portion of patients were able to receive treatment without a permanent intravenous catheter.

Navigating the Complexities of Infectious Disease

This study provides evidence supporting the effectiveness and feasibility of using ceftriaxone sodium as a single daily dose for 4 weeks in treating streptococcal endocarditis. The findings suggest that this regimen can be an effective and convenient treatment option for patients with this condition. However, it is essential to consult with a healthcare professional for appropriate diagnosis and treatment recommendations.

Dr.Camel's Conclusion

Just as a camel adapts to the harsh desert environment, our bodies can overcome infectious challenges. This study sheds light on a promising treatment for streptococcal endocarditis, demonstrating the effectiveness of ceftriaxone sodium administered as a single daily dose for 4 weeks. This research emphasizes the need for ongoing research to find optimal treatments for infectious diseases, improving patient outcomes and minimizing the impact of these conditions.

Date :
  1. Date Completed 1992-01-23
  2. Date Revised 2022-04-19
Further Info :

Pubmed ID

1727524

DOI: Digital Object Identifier

1727524

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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