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A randomized, single-blind comparison of topical clindamycin + benzoyl peroxide (Duac) and erythromycin + zinc acetate (Zineryt) in the treatment of mild to moderate facial acne vulgaris.

Author: LangnerA, LaytonA, Sheehan-DareR

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This assessor-blind, randomized study compared the clinical effectiveness of two combination treatments for facial acne: clindamycin phosphate (1%) plus benzoyl peroxide (5%) (CDP + BPO) and erythromycin (4%) plus zinc acetate (1.2%) (ERY + Zn). The study found that CDP + BPO showed an earlier onset of action with a faster significant reduction in total lesion counts than ERY + Zn.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Antibiotics are often combined with other agents to provide topical acne treatments that are effective against both inflammatory and non-inflammatory lesions and minimize the development of antibiotic resistance. OBJECTIVES: To compare the clinical effectiveness of two combination treat...See full text at original site
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引用元：
https://doi.org/10.1111/j.1468-3083.2006.01884.x

データ提供：米国国立医学図書館（NLM）

Acne Treatments: A Battle of the Creams

This study takes us on a journey into the [dermatology and skincare] realm, exploring the effectiveness of two different topical treatments for mild to moderate acne: clindamycin + benzoyl peroxide (Duac) and erythromycin + zinc acetate (Zineryt). The researchers conducted a randomized study to compare the two treatments, finding that Duac had a faster onset of action and a greater reduction in both inflammatory and non-inflammatory lesions. Both treatments were well-tolerated.

Duac's Early Advantage: A Speedy Solution in the Acne Desert

The study shows that Duac had a faster onset of action and a greater reduction in both inflammatory and non-inflammatory lesions compared to Zineryt. It's like finding a quicker route through the desert of acne, offering a faster solution to this common skin condition.

Finding the Right Treatment: A Personal Journey Through the Acne Desert

This research highlights the importance of finding the right treatment for acne based on individual needs and responses. It's like choosing the right camel for a journey through the desert of acne: some camels are better suited for specific terrains and challenges.

Dr.Camel's Conclusion

This research provides valuable information for dermatologists and patients struggling with acne. It's a reminder that with the right treatment and a little patience, we can navigate the challenges of acne and achieve clearer skin.

Date :
  1. Date Completed 2007-07-20
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

17309451

DOI: Digital Object Identifier

10.1111/j.1468-3083.2006.01884.x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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