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Vaginal absorption of low-dose tranexamic acid from impregnated tampons.

Author: CohenM, DevrajK, DuttonM, MoodleyJ

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Vaginal absorption of tranexamic acid (TA), an antifibrinolytic drug, was demonstrated in women with menorrhagia using TA-impregnated tampons. Low levels of TA were detected in the bloodstream, suggesting a potential alternative route of administration for the drug.
Paper Details　
Original Abstract of the Article :
Tranexamic acid (TA), an antifibrinolytic drug, is usually administered orally to women with menorrhagia. This route of administration is associated with adverse side-effects, therefore tampons impregnated with TA were used to assess the absorption of the drug across the vaginal epithelium. Blood le...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/1734554

データ提供：米国国立医学図書館（NLM）

Vaginal Absorption of Low-Dose Tranexamic Acid

This study investigated the vaginal absorption of low-dose tranexamic acid (TA) from impregnated tampons. The researchers found that TA was absorbed into the bloodstream in low concentrations when administered via impregnated tampons.

Vaginal Absorption of Tranexamic Acid

This study suggests that TA can be absorbed through the vaginal mucosa, potentially offering a more convenient and localized route of administration for certain conditions.

Understanding Tranexamic Acid

Tranexamic acid is commonly used to reduce heavy menstrual bleeding. Consulting with a healthcare professional is essential for understanding the potential benefits and risks of this medication and determining if it's appropriate for your specific needs.

Dr.Camel's Conclusion

Tranexamic acid, like a refreshing spring in a desert, can offer relief for heavy menstrual bleeding. This study suggests that a vaginal route of administration might be a viable option, offering a more localized and convenient approach. Remember, just as a desert traveler needs to be aware of the different water sources available, it's essential to consult with a healthcare professional to determine the best treatment plan for your individual needs.
Date :
  1. Date Completed 1992-02-28
  2. Date Revised 2014-09-12
Further Info :

Pubmed ID

1734554

DOI: Digital Object Identifier

1734554

SNS
PICO Info
in preparation
Languages

English

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