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Long-term effectiveness and quality of life improvement in entacapone-treated Parkinson's disease patients: the effects of an early therapeutic intervention.

Author: , GrandasF, HernándezB

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Entacapone, a drug used to treat Parkinson's disease, was effective in reducing motor fluctuations and improving quality of life. Early adjustment of entacapone and levodopa doses reduces the number of treatment discontinuations during the first months of treatment.
Paper Details　
Original Abstract of the Article :
To evaluate the long-term effects of entacapone on both mean daily 'on' time and health-related quality of life (QoL) in patients with Parkinson's disease (PD) experiencing 'end-of-dose' motor fluctuations and the benefits of an early therapeutic intervention. A prospective, multicenter, observation...See full text at original site
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引用元：
https://doi.org/10.1111/j.1468-1331.2006.01635.x

データ提供：米国国立医学図書館（NLM）

Entacapone: A Long-Term Solution for Parkinson's Disease

Parkinson's disease, a progressive neurological disorder, can significantly impact quality of life. This research explores the long-term effects of entacapone, a medication used to treat Parkinson's disease, on motor function and quality of life. It's like observing the effects of a carefully crafted potion on a traveler in a desert, monitoring their progress and well-being over time.

The study found that entacapone effectively reduced motor fluctuations, increased 'on' time, and improved quality of life in patients with Parkinson's disease. It's like witnessing the transformation of a weary traveler who finds a source of rejuvenation, restoring their strength and vitality.

Entacapone: A Long-Term Solution for Parkinson's Disease

The research suggests that entacapone, like a skilled healer, can provide a long-term solution for Parkinson's disease, offering a potential way to manage the disease's debilitating effects and improve quality of life. This is a significant development for individuals living with Parkinson's, offering hope for a more comfortable and fulfilling life.

The Importance of Early Intervention in Parkinson's Disease

The study highlights the importance of early intervention and dose adjustments in Parkinson's disease, recognizing that timely treatment can optimize outcomes and improve patient experiences. It's like recognizing the value of a timely and accurate diagnosis and treatment to prevent a disease from worsening.

Dr. Camel's Conclusion

This research provides a comprehensive assessment of the long-term effects of entacapone in treating Parkinson's disease. It's like witnessing the transformation of a desert landscape after a refreshing rain, revealing a renewed sense of hope and vitality. The study's findings highlight the potential of entacapone to improve quality of life and manage the disease's progression.

Date :
  1. Date Completed 2007-05-10
  2. Date Revised 2015-11-13
Further Info :

Pubmed ID

17355548

DOI: Digital Object Identifier

10.1111/j.1468-1331.2006.01635.x

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SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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