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Topiramate in the treatment of highly refractory patients with Dravet syndrome.

Author: ChironC, DulacO, Kröll-SegerJ, PortillaP

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Topiramate, an anticonvulsant drug, was helpful in treating Dravet syndrome, even in patients not satisfactorily controlled by stiripentol. Although it showed some efficacy in 78% of patients, it also showed poor tolerability in 17% of patients.
Paper Details　
Original Abstract of the Article :
The purpose of this study was to assess the effectiveness and tolerability of topiramate (TPM) as add-on therapy in children with Dravet syndrome and considered unsatisfactorily controlled using stiripentol. All the 36 patients having been treated with TPM in our centre in 2001 were retrospectively ...See full text at original site
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引用元：
https://doi.org/10.1055/s-2007-964867

データ提供：米国国立医学図書館（NLM）

Dravet Syndrome: A Desert Oasis of Hope

In the vast desert of Dravet syndrome research, this study offers a glimmer of hope for those who suffer from this debilitating condition. The authors, like intrepid explorers, sought to find a new route to [research objective], using a [research method] approach to uncover the effectiveness and safety of [treatment] in patients with Dravet syndrome. The study provides critical insights into the potential of [treatment] to improve the lives of individuals with Dravet syndrome.

A Beacon of Hope in the Storm

This study found that [key findings] which is a significant finding for [research field]. This research provides hope for those facing the challenges of Dravet syndrome, offering the potential for [potential benefits].

Navigating the Desert of Dravet Syndrome

This research highlights the importance of [recommendations for action] and underscores the need for continued research in this challenging area. The authors have provided a valuable map for navigating the desert of Dravet syndrome research, leading us towards a brighter future for patients with this condition.

Dr.Camel's Conclusion

Dravet syndrome is a difficult condition to treat, but this research offers a beacon of hope. The study shows that [treatment] may be a valuable addition to the arsenal of available therapies, offering potential benefits for patients. This is a significant step forward in our understanding of Dravet syndrome and its treatment, and it serves as a reminder that even in the most challenging deserts, there is always a chance for hope.

Date :
  1. Date Completed 2007-06-14
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

17357033

DOI: Digital Object Identifier

10.1055/s-2007-964867

Related Literature

Article Analysis
・Side Effects of stiripentol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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