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Cevimeline for the treatment of postirradiation xerostomia in patients with head and neck cancer.
Author: ArmstrongIngrid, BielMerrill A, ChambersMark S, HodgeKenneth M, JonesChristopher Uwe, PosnerMarshall, VittiRobert, WeberRandal S, YenCindy
Original Abstract of the Article :
PURPOSE: To study the efficacy and safety of cevimeline in two double-blind trials (Studies 003 and 004) enrolling patients with head and neck cancer in whom xerostomia developed after radiotherapy. METHODS AND MATERIALS: Subjects were randomly assigned to receive cevimeline, 30 mg three times dail...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.ijrobp.2007.01.019
データ提供:米国国立医学図書館(NLM)
A Sip of Relief: Cevimeline for Xerostomia
This research delves into the realm of [xerostomia], a condition that can leave you feeling like a camel in the Sahara Desert with a parched throat. It explores the efficacy and safety of [cevimeline] in treating xerostomia, a common side effect of [radiotherapy] for head and neck cancer.Quenching the Thirst: Cevimeline's Impact
The study found that [cevimeline] was well-tolerated by patients and significantly increased [unstimulated salivary flow], which is the body's natural way of keeping the mouth moist. This finding suggests that cevimeline can help to alleviate the discomfort of xerostomia and improve the quality of life for patients who have undergone radiotherapy.A Glimpse of Hope in the Desert
This research offers hope for patients struggling with xerostomia, a condition that can significantly impact their quality of life. The study underscores the importance of finding effective treatments for side effects of cancer therapies and the need to explore alternative approaches to managing xerostomia.Health Implications and Everyday Life
Xerostomia is a common side effect of various medical treatments, not just radiotherapy. If you experience dry mouth, it's important to consult with your healthcare provider to discuss potential causes and treatment options. Simple strategies like sipping water frequently, chewing sugar-free gum, and using artificial saliva can also provide relief.Dr.Camel's Conclusion
This research highlights the importance of finding effective treatments for side effects of medical treatments. It's a reminder that even in the face of challenging medical conditions, there are options available to improve quality of life and make everyday living more comfortable.Date :
- Date Completed 2007-08-06
- Date Revised 2012-11-15
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