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Treatment of newly diagnosed symptomatic pure low-grade oligodendrogliomas with PCV chemotherapy.

Author: BourgV, ChanaletS, FauchonF, FontaineD, FrenayM, LebrunC, LonjonM, PaquisP, RamaioliA, VandenbosF

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study reported the outcome of 33 consecutive patients with pure low-grade OG treated with PCV chemotherapy after surgery. Up-front chemotherapy with PCV regimen was found to be a good treatment for symptomatic pure low-grade OG, increasing the number of progression-free patients and time to progression.
Paper Details　
Original Abstract of the Article :
Based on studies relating to anaplastic oligodendroglioma (OG) chemosensitivity and benefit of time to progression or overall survival, chemotherapy for pure OG has been proposed. Several studies have reported the efficacy of various chemotherapeutic agents in a small number of patients with low-gra...See full text at original site
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引用元：
https://doi.org/10.1111/j.1468-1331.2007.01675.x

データ提供：米国国立医学図書館（NLM）

Chemotherapy for Newly Diagnosed Pure Low-Grade Oligodendrogliomas

Navigating the complexities of brain tumors can be like searching for a hidden oasis in a vast desert. This research investigates the effectiveness of PCV chemotherapy for patients newly diagnosed with pure low-grade oligodendrogliomas (OG). The study included 33 patients who received PCV chemotherapy as the first-line treatment after surgery. The results show a significant improvement in progression-free survival, with 90% of patients being progression-free at 1 year. The study also highlights the potential to delay radiotherapy until malignant transformation occurs, minimizing cognitive side effects.

PCV Chemotherapy Shows Promise in Treating Low-Grade Oligodendrogliomas

This study provides compelling evidence for the efficacy of PCV chemotherapy in treating newly diagnosed pure low-grade OG. The findings demonstrate a significant improvement in progression-free survival, suggesting that PCV chemotherapy could be a valuable treatment option for patients with this type of tumor. The study's findings on delaying radiotherapy also offer a potential strategy for mitigating cognitive side effects.

Understanding Brain Tumors: Seeking Early Diagnosis and Treatment

Brain tumors can be complex and challenging to treat. Early diagnosis and prompt treatment are essential for improving outcomes. If you experience any neurological symptoms, it's important to consult with a healthcare provider for a thorough evaluation. Don't hesitate to seek medical attention if you have concerns about your health.

Dr. Camel's Conclusion

This research sheds light on the potential benefits of PCV chemotherapy in treating newly diagnosed pure low-grade OG. The findings offer a glimmer of hope for patients with this type of tumor, suggesting that PCV chemotherapy could significantly improve progression-free survival. The study also underscores the importance of personalized treatment strategies that minimize potential side effects and optimize patient outcomes.
Date :
  1. Date Completed 2007-06-13
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

17388986

DOI: Digital Object Identifier

10.1111/j.1468-1331.2007.01675.x

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English

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