Comparison of the local anesthetic effects of chlorpheniramine, midazolam, lidocaine, and normal saline after intradermal injection.

Author: BilginFerruh, DoğrulAhmet, OrhanMehmet Emin, YükselUğur

Paper Details 
Original Abstract of the Article :
Local anesthetic effects of antihistamines are well known, but have been tested more for diphenhydramine than for chlorpheniramine. Midazolam, a benzodiazepine gamma-aminobutyric acid type A receptor agonist, induces spinally mediated analgesia. However, the local anesthetic effects of chlorpheniram...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/17392658

データ提供:米国国立医学図書館(NLM)

Comparing Local Anesthetics: A Quest for Pain Relief

In the world of pain management, researchers are constantly seeking to understand the mechanisms of local anesthetics and optimize their effectiveness. This study delves into the local anesthetic effects of chlorpheniramine, midazolam, lidocaine, and normal saline after intradermal injection, comparing their ability to reduce infiltration pain and provide local anesthetic effects. The authors embark on a journey to understand the relative merits of these agents.

Unveiling the Local Anesthetic Properties of Chlorpheniramine and Midazolam

The study meticulously examines the local anesthetic effects of chlorpheniramine and midazolam, comparing them to the well-established anesthetic properties of lidocaine and the control group receiving normal saline. This comparative analysis, like a desert expedition seeking a hidden oasis of knowledge, aims to shed light on the potential for these agents to provide effective pain relief.

A New Perspective on Local Anesthetics: Exploring the Potential of Antihistamines and Benzodiazepines

This study, like a sand dune revealing a hidden treasure, highlights the potential of antihistamines and benzodiazepines to provide local anesthetic effects. It provides valuable data to support their use in pain management, offering a new perspective on the range of agents available for pain relief.

Dr.Camel's Conclusion

This study, like a caravan navigating the vast desert of pain management research, offers valuable insights into the local anesthetic properties of chlorpheniramine and midazolam. It suggests that these agents, often used for different purposes, may hold potential for pain relief, expanding the options available for patients seeking effective pain management.

Date :
  1. Date Completed 2008-03-06
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

17392658

DOI: Digital Object Identifier

6577

Related Literature

SNS
PICO Info
in preparation
Languages

English

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