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Three-year calcitonin combination therapy for postmenopausal osteoporosis with crush fractures of the spine.

Author: HollóI, HorváthC, KollinE, SzathmáriM, SzücsJ

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study of 45 postmenopausal women with osteoporosis and vertebral fractures compared three treatment groups: calcitonin and calcium, calcitonin, calcium, and phosphate, and calcitonin, calcium, and norandrostenolone decanoate. Calcitonin alone effectively prevented further bone loss for 24 months. Phosphate supplementation was not beneficial. The combination of calcitonin and norandrostenolone decanoate extended bone-preserving effects for 36 months. This suggests that the combination of calcitonin and norandrostenolone decanoate may be a promising and cost-effective treatment for established postmenopausal osteoporosis.
Paper Details　
Original Abstract of the Article :
Forty-five postmenopausal osteoporotic women with at least one osteoporotic vertebral crush fracture were randomized into three treatment groups. Each patient was on calcitonin, 50 U, on alternate days for 2 weeks monthly (350 U/month), and 500 mg/day oral calcium supplementation. In group II, this ...See full text at original site
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引用元：
https://doi.org/10.1007/BF00297289

データ提供：米国国立医学図書館（NLM）

Combating Osteoporosis: A Multifaceted Approach

Osteoporosis, a disease characterized by weakened bones, is a major concern for postmenopausal women, increasing their risk of fractures. This research explores the efficacy of different therapeutic regimens in treating postmenopausal osteoporosis, particularly in women with vertebral crush fractures.

The authors conducted a randomized clinical trial to compare the effectiveness of calcitonin therapy alone, calcitonin with phosphate supplementation, and calcitonin with norandrostenolone decanoate in treating postmenopausal osteoporosis. Their findings provide valuable insights into the potential benefits and limitations of these treatment options.

Strengthening Bones: A Promising Combination

The research suggests that combining calcitonin with the anabolic steroid norandrostenolone decanoate may be a promising and relatively inexpensive treatment regimen for postmenopausal osteoporosis. This combination showed extended efficacy over a 36-month period, demonstrating its potential to prevent further bone loss and promote bone health.

Healthy Bones: A Lifelong Commitment

This research emphasizes the importance of early diagnosis and treatment for postmenopausal osteoporosis. It highlights the need for personalized treatment plans, considering individual patient characteristics and potential risks and benefits of various therapies. It also underscores the importance of healthy lifestyle choices, including regular exercise and a balanced diet, to maintain bone health throughout life.

Dr.Camel's Conclusion

Just as a camel's strong bones allow it to navigate harsh desert landscapes, strong bones are essential for maintaining mobility and independence. This research highlights the importance of effective treatment options for postmenopausal osteoporosis, providing valuable insights for healthcare providers and patients alike.

Date :
  1. Date Completed 1992-03-20
  2. Date Revised 2019-08-27
Further Info :

Pubmed ID

1739873

DOI: Digital Object Identifier

10.1007/BF00297289

Related Literature

Article Analysis
・Effective treatment of osteoporosis
SNS
PICO Info
in preparation
Languages

English

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