Multi-objective optimization of an industrial penicillin V bioreactor train using non-dominated sorting genetic algorithm.

Author: LeeFook Choon, RangaiahGade Pandu, RayAjay Kumar

Paper Details 
Original Abstract of the Article :
Bulk of the penicillin produced is used as raw material for semi-synthetic penicillin (such as amoxicillin and ampicillin) and semi-synthetic cephalosporins (such as cephalexin and cefadroxil). In the present paper, an industrial penicillin V bioreactor train is optimized for multiple objectives sim...See full text at original site
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引用元:
https://doi.org/10.1002/bit.21443

データ提供:米国国立医学図書館(NLM)

Optimizing Penicillin V Production: A Journey Through the Desert of Bioreactors

The desert of industrial biotechnology is a complex landscape, with bioreactors acting like oases where valuable products are cultivated. This study explores the multi-objective optimization of an industrial penicillin V bioreactor train, like a skilled camel guide seeking the most efficient route to maximize production.

Finding the Optimal Oasis: A Multi-Objective Approach

The researchers used a sophisticated genetic algorithm to optimize the bioreactor train, much like a camel guide carefully selecting the best route to maximize both speed and efficiency. Their findings reveal a range of optimal design and operating conditions, highlighting the complex interplay of factors that influence production efficiency, like understanding the delicate balance of forces in a shifting sandstorm. This research offers valuable insights for improving the production of penicillin V, a vital antibiotic used to combat bacterial infections.

A Camel's Guide to Industrial Biotechnology: Maximizing Efficiency

This study underscores the importance of a multi-objective approach to optimizing industrial processes. It's like a camel guide ensuring that the caravan is equipped with the best supplies and strategies to navigate the challenges of a vast desert. This research demonstrates the power of advanced algorithms to achieve significant improvements in production efficiency, offering a potential oasis of innovation in the field of industrial biotechnology.

Dr. Camel's Conclusion

This study explores the multi-objective optimization of an industrial penicillin V bioreactor train, like a skilled camel guide seeking the most efficient route through the desert of industrial biotechnology. The researchers' findings highlight the potential of advanced algorithms to improve production efficiency, offering a path to greater sustainability and cost-effectiveness. This research underscores the importance of continuous innovation and optimization in the pursuit of maximizing production and meeting the world's growing demand for essential medications.

Date :
  1. Date Completed 2007-11-13
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

17405176

DOI: Digital Object Identifier

10.1002/bit.21443

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Languages

English

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