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Evaluation of human immunodeficiency virus type 1-infected Chinese patients treated with highly active antiretroviral therapy for two years.

Author: ChenJun, DingPei-Pei, HeYan, LiHui, ZhangChun-Ying, ZhengYu-Huang, ZhouHua-Ying

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study evaluated the long-term efficacy and safety of nevirapine in combination with didanosine and stavudine for treating HIV-infected Chinese patients. After 24 months, 56.6% of patients achieved viral load suppression. CD4 T cell counts increased significantly, but activated CD8(+) T cells remained elevated. The regimen was well tolerated.
Paper Details　
Original Abstract of the Article :
The purpose of this study was to evaluate the long-term efficacy and safety of nevirapine in combination with didanosine and stavudine in the treatment of human immunodeficiency virus (HIV)1-infected Chinese patients in routine clinical practice. The study, from April 2003 to May 2005, with follow-u...See full text at original site
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引用元：
https://doi.org/10.1089/vim.2006.0047

データ提供：米国国立医学図書館（NLM）

Long-Term Efficacy of HAART: A Two-Year Journey for HIV-Infected Patients

The field of HIV treatment has undergone a remarkable transformation, with highly active antiretroviral therapy (HAART) providing a lifeline to infected individuals. This study evaluates the long-term efficacy and safety of a specific HAART regimen in a group of Chinese patients.

The study analyzed data from 27 HIV-infected patients who received a combination of didanosine, stavudine, and nevirapine for 24 months. The results showed that the regimen achieved durable viral suppression in a significant number of patients, with a notable increase in CD4 cell count. The study also demonstrated the overall tolerability of the regimen, with only a few patients experiencing side effects that led to treatment discontinuation.

HAART: A Durable Oasis in the Desert of HIV Treatment

The study's findings offer encouraging evidence for the long-term effectiveness of HAART in managing HIV infection. The positive outcomes and overall tolerability of the regimen provide hope for improving the lives of HIV-infected individuals.

Navigating the Shifting Sands of HIV Treatment: A Long-Term Perspective

This study underscores the importance of long-term monitoring and management for HIV-infected patients. It highlights the effectiveness of HAART in controlling viral load and improving immune function, offering a beacon of hope for individuals living with HIV.

Dr.Camel's Conclusion

The desert of HIV treatment is vast and unforgiving, but HAART offers a precious oasis for those seeking relief. This study provides evidence of the long-term benefits of a specific HAART regimen, reminding us that with ongoing care and management, HIV-infected individuals can live longer, healthier lives.

Date :
  1. Date Completed 2007-05-11
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

17425432

DOI: Digital Object Identifier

10.1089/vim.2006.0047

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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