Paper Details

  1. Home
  2. Paper Details

Ceftibuten versus cefaclor for the treatment of bronchitis.

Author: AikenS, CassanoK B, ChirurgiV A, EdelsteinH, KarpR, KrumpeP, McCabeR E, OsterS E

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, U.S. Gov't, Non-P.H.S.Research funding provided by US government agencies other than the Public Health Service.

Overview

Ceftibuten, a third-generation cephalosporin, was as effective and safe as cefaclor in treating bronchitis. In a small study of 58 patients, 87.5% of those treated with ceftibuten and 92.3% of those treated with cefaclor showed clinical improvement or cure. Adverse effects were reported in 7.9% of the ceftibuten group and 5.6% of the cefaclor group.
Paper Details　
Original Abstract of the Article :
Ceftibuten is an oral third generation cephalosporin with potent antimicrobial activity against Enterobacteriaceae, beta-lactamase positive Haemophilus influenzae, Moraxella catarrhalis, Neisseria meningitidis, Neisseria gonorrheae, penicillin-susceptible pneumococci, and beta-hemolytic streptococci...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1093/jac/28.4.577

データ提供：米国国立医学図書館（NLM）

Ceftibuten vs. Cefaclor: Two Antibiotics in the Desert of Bronchitis

Bronchitis, a common respiratory ailment, can be a challenging condition to navigate. This study compares the effectiveness of two antibiotics, ceftibuten and cefaclor, in treating bronchitis. The researchers enrolled 58 patients and randomly assigned them to receive either ceftibuten or cefaclor. They discovered that both antibiotics were equally effective in treating bronchitis, with a similar number of patients experiencing clinical improvement or cure. This is like finding two reliable oases in a vast desert, both offering respite from the scorching heat of bronchitis.

An Oasis of Effective Treatment

The study's findings suggest that both ceftibuten and cefaclor are effective options for treating bronchitis. The similar rates of clinical improvement and cure in both treatment groups provide a reassuring beacon of hope for patients seeking relief from bronchitis. This is like discovering two equally nourishing springs in a desert, both offering essential hydration and relief.

Navigating the Antibiotic Landscape

The study's findings highlight the importance of choosing the right antibiotic for treating bronchitis. While both ceftibuten and cefaclor were effective in this study, individual patient factors, such as allergies and potential drug interactions, should be carefully considered when selecting the appropriate treatment. Like a desert explorer, we must always be mindful of the nuances of our environment and make informed decisions based on the specific circumstances of each patient.

Dr. Camel's Conclusion

This study provides valuable insights into the effectiveness of ceftibuten and cefaclor in treating bronchitis. The discovery that both antibiotics are equally effective in this ailment is a reassuring oasis in the vast desert of respiratory infections. However, as with any desert journey, we must be mindful of the unique needs of each patient and select the most appropriate antibiotic for their specific situation.

Date :
  1. Date Completed 1992-02-13
  2. Date Revised 2019-05-10
Further Info :

Pubmed ID

1761452

DOI: Digital Object Identifier

10.1093/jac/28.4.577

Related Literature

Article Analysis
・Effects of ceftibuten・Effects of cefpodoxime
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.