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Original Abstract of the Article :
The use of previous anorectic medications and the combined use of the anorectic medications fenfluramine and phentermine (Fen-Phen) have been associated with varying degrees of valvular regurgitation and pulmonary hypertension. More recent reports have suggested a lower incidence of both than was pr...See full text at original site
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引用元:
https://doi.org/10.1177/0003319707302496
データ提供:米国国立医学図書館(NLM)
The Long Shadow of Fenfluramine-Phentermine
The use of fenfluramine-phentermine (Fen-Phen), a weight-loss medication, has been linked to valvular regurgitation and pulmonary hypertension. While the incidence of these complications has been reported to be lower than initially thought, the long-term effects of Fen-Phen remain a concern. This study, conducted in the field of cardiology, examined the longitudinal effects of Fen-Phen on cardiac function and hemodynamics. The researchers found that Fen-Phen was associated with significant valvular regurgitation and elevated pulmonary artery pressures, even after discontinuation of the medication. Furthermore, the study identified long-term changes in heart chambers and ejection fractions, suggesting a potential for persistent cardiac effects.
A Long-Term Impact on the Heart
The study's findings paint a complex picture of the long-term consequences of Fen-Phen use. While the incidence of valvular regurgitation and pulmonary hypertension appears to decrease over time, the study highlights the potential for persistent cardiac abnormalities, even after discontinuation of the medication. This information is crucial for guiding future clinical decisions and addressing potential long-term risks for individuals who have used Fen-Phen. It's a reminder that the desert of the heart can be a dangerous place, with long-lasting effects from past experiences.
Navigating the Desert of Cardiac Health
For those who have used Fen-Phen in the past, it's essential to be aware of the potential for long-term cardiac effects. Regular cardiac monitoring is recommended to identify any potential complications early. This research highlights the importance of considering the long-term consequences of medication use and the need for close follow-up care. It's a reminder to always approach the desert of the heart with caution and awareness.
Dr.Camel's Conclusion
This study provides valuable insights into the long-term effects of Fen-Phen use on cardiac function. The findings emphasize the potential for persistent cardiac abnormalities, even after discontinuation of the medication. This research underscores the importance of considering the long-term consequences of medication use and the need for close follow-up care. It's a reminder that the desert of the heart can be a complex and unpredictable place, where the echoes of past experiences can linger for a long time.
Date :
- Date Completed 2007-08-02
- Date Revised 2016-11-24
Further Info :
Related Literature
English
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