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Buprenorphine injection to the stellate ganglion in the treatment of upper body chronic pain syndromes.

Author: AllenSteve, GlynnChris, GoebelAndreas, LawsonAndrew

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

GLOA, Ganglionide Local Opioid Analgesia, is used to treat chronic pain. This study assessed whether GLOA was more efficacious than SSB, saline injection to the stellate plus intramuscular buprenorphine.
Paper Details　
Original Abstract of the Article :
The injection of low dose buprenorphine to the sympathetic ganglia, termed "GLOA", Ganglionide Local Opioid Analgesia, is used to treat chronic pain in several European centres. It is not known whether the clinically observed GLOA effect in chronic pain syndromes is due to a specific effect of bupre...See full text at original site
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引用元：
https://doi.org/10.1016/j.ejpain.2007.05.009

データ提供：米国国立医学図書館（NLM）

A Novel Approach to Chronic Pain: Ganglionide Local Opioid Analgesia (GLOA)

The [treatment of chronic pain syndromes] presents a formidable challenge. This study explores a novel approach: [Ganglionide Local Opioid Analgesia (GLOA)], which involves injecting a low dose of [buprenorphine] into the [sympathetic ganglia]. The researchers adopted a [comparative study] to determine the efficacy of GLOA compared to a reverse approach, termed SSB. This research seeks to shed light on the true nature of GLOA's effectiveness, exploring whether the observed pain relief is a result of the buprenorphine's action at the ganglia or a more general effect.

Unlocking the Mystery of GLOA: An Examination of Efficacy

This study provides a detailed comparison between [GLOA and SSB] in the context of chronic pain syndromes. The results reveal the efficacy of GLOA in alleviating chronic pain, but the study also raises a crucial question: [Is the pain relief a result of buprenorphine's specific action at the ganglia or a more general effect?]. The findings underscore the need for further investigation to pinpoint the exact mechanism underlying GLOA's effectiveness.

A Journey Through the Desert of Pain: Seeking Relief

This research offers a glimmer of hope for individuals enduring the relentless burden of [chronic pain syndromes]. By exploring the potential of [GLOA], this study sheds light on a promising new avenue for pain relief. It's like finding a hidden oasis in the heart of the desert, offering a respite from the scorching sun and the relentless sandstorms of pain.

Dr.Camel's Conclusion

This study delves into the exciting potential of [GLOA] as a novel approach to managing chronic pain. While further research is needed to fully understand the mechanism underlying its effectiveness, this study offers a promising glimpse into a future where individuals can find relief from debilitating pain. It's like discovering a secret path through the desert, leading to a hidden oasis of comfort and serenity.

Date :
  1. Date Completed 2008-04-28
  2. Date Revised 2014-07-30
Further Info :

Pubmed ID

17638583

DOI: Digital Object Identifier

10.1016/j.ejpain.2007.05.009

Related Literature

Article Analysis
・Effects of buprenorphine injection (pain relief)
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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