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The effects of high dose pravastatin and low dose pravastatin and ezetimibe combination therapy on lipid, glucose metabolism and inflammation.
Author: DagliNecati, KaracaIlgin, YavuzkirMustafa
Original Abstract of the Article :
Coronary artery disease (CAD) is presently the major cause of mortality and morbidity. Anti-hyperlipidemic treatment is one of the main treatment steps in the management of CAD. Statins are the cornerstones in this treatment. Ezetimibe can be reliably used, when statins prove ineffective in treatmen...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1007/s10753-007-9041-3
データ提供:米国国立医学図書館(NLM)
Navigating the Desert of Cholesterol: Exploring Statin and Ezetimibe Combinations
The [treatment of coronary artery disease (CAD)] is a complex journey across the desert of cardiovascular health. This study delves into the use of [statins], like [pravastatin], and [ezetimibe], a drug that lowers cholesterol absorption, to manage [CAD]. The researchers explored the effects of [high-dose pravastatin (40 mg) and low-dose pravastatin (10 mg) + ezetimibe (10 mg) combination therapy] on [lipid and glucose mechanism, as well as inflammation].
A New Path Through the Desert of Cholesterol
The researchers found that [both high-dose pravastatin and the combination therapy] were effective in [reducing cholesterol levels and improving lipid profiles]. These findings, like a well-stocked caravan with supplies for the journey, suggest that these treatments could be valuable tools in the fight against [CAD].
A Balanced Approach to Cholesterol Management
This study, like a guidebook for navigating the desert, highlights the importance of finding the [optimal balance] between [statins] and [ezetimibe]. This could help to maximize the benefits of these treatments while minimizing potential side effects.
Dr.Camel's Conclusion
The research on [statin and ezetimibe combinations] provides a valuable roadmap for navigating the desert of [cholesterol management]. By understanding the nuances of these treatments, clinicians can develop personalized approaches that maximize patient outcomes and improve cardiovascular health.
Date :
- Date Completed 2008-02-14
- Date Revised 2018-11-13
Further Info :
Related Literature
English
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