The effects of high dose pravastatin and low dose pravastatin and ezetimibe combination therapy on lipid, glucose metabolism and inflammation.

Author: DagliNecati, KaracaIlgin, YavuzkirMustafa

Paper Details 
Original Abstract of the Article :
Coronary artery disease (CAD) is presently the major cause of mortality and morbidity. Anti-hyperlipidemic treatment is one of the main treatment steps in the management of CAD. Statins are the cornerstones in this treatment. Ezetimibe can be reliably used, when statins prove ineffective in treatmen...See full text at original site
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引用元:
https://doi.org/10.1007/s10753-007-9041-3

データ提供:米国国立医学図書館(NLM)

Navigating the Desert of Cholesterol: Exploring Statin and Ezetimibe Combinations

The [treatment of coronary artery disease (CAD)] is a complex journey across the desert of cardiovascular health. This study delves into the use of [statins], like [pravastatin], and [ezetimibe], a drug that lowers cholesterol absorption, to manage [CAD]. The researchers explored the effects of [high-dose pravastatin (40 mg) and low-dose pravastatin (10 mg) + ezetimibe (10 mg) combination therapy] on [lipid and glucose mechanism, as well as inflammation].

A New Path Through the Desert of Cholesterol

The researchers found that [both high-dose pravastatin and the combination therapy] were effective in [reducing cholesterol levels and improving lipid profiles]. These findings, like a well-stocked caravan with supplies for the journey, suggest that these treatments could be valuable tools in the fight against [CAD].

A Balanced Approach to Cholesterol Management

This study, like a guidebook for navigating the desert, highlights the importance of finding the [optimal balance] between [statins] and [ezetimibe]. This could help to maximize the benefits of these treatments while minimizing potential side effects.

Dr.Camel's Conclusion

The research on [statin and ezetimibe combinations] provides a valuable roadmap for navigating the desert of [cholesterol management]. By understanding the nuances of these treatments, clinicians can develop personalized approaches that maximize patient outcomes and improve cardiovascular health.

Date :
  1. Date Completed 2008-02-14
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

17687635

DOI: Digital Object Identifier

10.1007/s10753-007-9041-3

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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