Duration of action of topical antiallergy drugs in a Guinea pig model of histamine-induced conjunctival vascular permeability.

Author: BeauregardClay, GamacheDaniel, RobertsLeighann, StephensDonna, YanniJohn

Paper Details 
Original Abstract of the Article :
The topical application of 0.1% olopatadine has been shown to provide significant attenuation of histamine-induced conjunctival vascular permeability (CVP) within 5 min and for as long as 24 h following a topical administration. The duration of the action of olopatadine was compared to that of epina...See full text at original site
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引用元:
https://doi.org/10.1089/jop.2006.0138

データ提供:米国国立医学図書館(NLM)

Olopatadine: A Long-Lasting Solution for Allergic Conjunctivitis

Allergic conjunctivitis is a common condition that can cause itchy, watery eyes. This research investigates the duration of action of olopatadine, a topical antiallergic drug, in a guinea pig model of histamine-induced conjunctival vascular permeability. The study compares the effectiveness of olopatadine to that of other antiallergic drugs, such as epinastine, azelastine, and ketotifen.

Olopatadine's Lasting Effects: A Relief for Itchy Eyes

The researchers found that olopatadine was significantly effective in inhibiting histamine-induced vascular permeability for up to 16 hours after a single topical application, significantly longer than the other drugs tested. This suggests that olopatadine could offer a longer-lasting relief for individuals with allergic conjunctivitis.

Navigating the Desert of Allergy Relief

This research provides valuable insights into the search for effective treatments for allergic conjunctivitis. Imagine a traveler navigating a vast desert, where the sun's glare and dry air can cause irritation and discomfort. Just as a traveler seeks protection from the elements, individuals with allergic conjunctivitis seek relief from the symptoms of their condition. Olopatadine, like a cool oasis, may provide a longer-lasting respite from the discomfort of itchy eyes.

Dr. Camel's Conclusion

This research delves into the world of allergic conjunctivitis, a condition that can significantly impact quality of life. The findings highlight the potential of olopatadine as a long-lasting solution for managing this common condition. The study serves as a reminder that the quest for effective allergy treatments is an ongoing journey, with the goal of improving comfort and well-being for those affected by allergies.

Date :
  1. Date Completed 2007-11-08
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

17803429

DOI: Digital Object Identifier

10.1089/jop.2006.0138

Related Literature

SNS
PICO Info
in preparation
Languages

English

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