Paper Details 
Original Abstract of the Article :
Transdermal absorption of lidocaine was determined by measuring plasma lidocaine concentrations following skin application of 5% lidocaine patches. Two lidocaine patches were placed on the ventral abdominal midline of seven dogs for 72 hours. Lidocaine was detectable in plasma 12 hours after patch a...See full text at original site
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引用元:
https://doi.org/10.5326/0430280

データ提供:米国国立医学図書館(NLM)

Lidocaine Patch Application: Measuring Drug Absorption in Dogs

This study explores the transdermal absorption of lidocaine in dogs by measuring plasma lidocaine concentrations after applying a 5% lidocaine patch. It's like studying how a camel absorbs water from a moist oasis, understanding the process of how the drug enters the bloodstream.

The study found that lidocaine was detectable in the blood 12 hours after patch application, reaching steady-state concentrations between 24 and 48 hours. It's like observing a camel slowly but surely rehydrating after reaching an oasis. The study also showed that plasma lidocaine levels decreased significantly after 60 hours post-application, and low concentrations remained for 6 hours after patch removal. This is like observing the camel's body slowly returning to its normal state after quenching its thirst.

Transdermal Absorption of Lidocaine: A New Frontier in Drug Delivery

This study demonstrates the potential for transdermal drug delivery using lidocaine patches. It's like finding a new way to deliver water to camels in the desert, a more efficient and convenient method. This approach can be beneficial for both animals and humans, offering a less invasive and potentially more effective way to administer certain medications.

Exploring Drug Delivery Methods: A Continuous Quest

This study is a reminder that the desert of medical research is vast and full of exciting possibilities. We continue to explore new and innovative ways to deliver medications effectively and safely. This research is a testament to the ingenuity and dedication of scientists who are constantly seeking better ways to improve health and well-being.

Dr. Camel's Conclusion

This study provides valuable insights into the transdermal absorption of lidocaine in dogs. It's a reminder that the desert of medical research is constantly evolving, and we need to remain open to new ideas and approaches to improve healthcare. By embracing innovation and collaboration, we can create a healthier and more sustainable future for all.

Date :
  1. Date Completed 2007-09-21
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

17823477

DOI: Digital Object Identifier

10.5326/0430280

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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