Efficacy and tolerability of adding prescription omega-3 fatty acids 4 g/d to simvastatin 40 mg/d in hypertriglyceridemic patients: an 8-week, randomized, double-blind, placebo-controlled study.

Author: , BallantyneChristie M, BaysHarold E, DavidsonMichael H, DoyleRalph T, GinsbergHenry N, MakiKevin C, ShalwitzRobert A, SteinEvan A

Paper Details 
Original Abstract of the Article :
Patients with elevated serum triglyceride (TG) levels often have elevations in non-high-density lipoprotein cholesterol (non-HDL-C) levels as well. The National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) has identified non-HDL-C as a secondary therapeutic target in these ...See full text at original site
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引用元:
https://doi.org/10.1016/j.clinthera.2007.07.018

データ提供:米国国立医学図書館(NLM)

A Multifaceted Approach to Managing Hypertriglyceridemia

Hypertriglyceridemia, a condition characterized by elevated triglyceride levels in the blood, is a common health concern. This study explores the potential benefits of adding prescription omega-3 fatty acids to simvastatin therapy in patients with hypertriglyceridemia. The researchers conducted an eight-week randomized, double-blind, placebo-controlled study involving patients with elevated serum triglyceride (TG) levels. They found that adding omega-3 fatty acids to simvastatin therapy resulted in significant reductions in both TG and non-high-density lipoprotein cholesterol (non-HDL-C) levels, demonstrating the potential of this combination therapy for managing hypertriglyceridemia. This research highlights the importance of a multifaceted approach to managing hypertriglyceridemia, incorporating both medication and lifestyle modifications.

The Importance of Combining Medications and Lifestyle Modifications

This study underscores the importance of combining medications and lifestyle modifications to effectively manage hypertriglyceridemia. While statins are effective in lowering cholesterol levels, they may not be sufficient to achieve optimal lipid profiles in all patients, especially those with high TG levels. The addition of omega-3 fatty acids demonstrates the potential of combining medications with lifestyle interventions to achieve better outcomes for patients with hypertriglyceridemia.

The Importance of Addressing Lipid Levels in Cardiovascular Health

The study's findings highlight the importance of addressing lipid levels, including both cholesterol and triglycerides, for optimal cardiovascular health. Elevated TG levels are associated with an increased risk of cardiovascular disease, emphasizing the need for comprehensive management strategies that target both cholesterol and triglyceride levels. This research underscores the importance of ongoing monitoring and management of lipid levels to reduce the risk of cardiovascular disease.

Dr. Camel's Conclusion

Just like a camel navigating a desert, managing hypertriglyceridemia requires a multifaceted approach. This study offers a valuable guide, highlighting the benefits of combining medication and lifestyle modifications. By embracing a comprehensive approach to cardiovascular health, we can help individuals navigate the desert of high lipid levels and reach their health goals.

Date :
  1. Date Completed 2007-10-09
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

17825687

DOI: Digital Object Identifier

10.1016/j.clinthera.2007.07.018

Related Literature

SNS
PICO Info
in preparation
Languages

English

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