Treatment of hepatitis B e antigen positive chronic hepatitis with telbivudine or adefovir: a randomized trial.

Author: , BrownNathaniel A, BzowejNatalie, ChanHenry L Y, ChaoYou-Chen, ChoMong, HarbGeorge, HeathcoteE Jenny, JeffersLennox, KaiserRalf, LaiChing-Lung, MarcellinPatrick, MinukGerald Y, MoonYoung M, MyersRobert P, QiaoXin-Jian, SievertWilliam

Paper Details 
Original Abstract of the Article :
BACKGROUND: The efficacy of nucleoside and nucleotide analogues for hepatitis B has been linked to the magnitude and durability of hepatitis B virus (HBV) suppression. OBJECTIVE: To compare the antiviral efficacy of telbivudine and adefovir dipivoxil, and the effects of switching from adefovir to t...See full text at original site
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引用元:
https://doi.org/10.7326/0003-4819-147-11-200712040-00183

データ提供:米国国立医学図書館(NLM)

Treatment of Hepatitis B e Antigen Positive Chronic Hepatitis: A Comparative Study of Telbivudine and Adefovir

The field of [hepatitis B] treatment is continually seeking new and effective therapies to combat this viral infection. This research explores the efficacy of two antiviral medications, [telbivudine] and [adefovir dipivoxil], in patients with [hepatitis B e antigen (HBeAg)-positive chronic hepatitis B]. The authors conducted a randomized controlled trial, comparing the antiviral efficacy of these two medications and investigating the effects of switching from [adefovir] to [telbivudine]. Their findings provide valuable insights into the relative effectiveness of these medications and offer guidance for clinicians managing patients with [chronic hepatitis B].

Telbivudine: A Promising Treatment Option for Hepatitis B

The findings of this study suggest that [telbivudine] may be a more effective treatment option for [HBeAg-positive chronic hepatitis B] compared to [adefovir]. [Telbivudine] demonstrated greater and more consistent [HBV DNA] suppression than [adefovir] after 24 weeks of treatment. This research highlights the potential of [telbivudine] to improve treatment outcomes for patients with [chronic hepatitis B], offering a potentially more effective and durable antiviral therapy.

Living with Hepatitis B: A Journey Towards Health

[Hepatitis B] is a serious condition, but advancements in treatment offer hope for patients. This research underscores the importance of seeking early diagnosis and treatment to maximize the potential for successful outcomes. By working closely with healthcare professionals and following treatment plans, patients with [hepatitis B] can manage their condition and strive for a healthier future. This research offers a beacon of hope for patients with [hepatitis B], highlighting the potential for effective treatment and improved quality of life.

Dr. Camel's Conclusion

This research on the treatment of [hepatitis B e antigen positive chronic hepatitis] with [telbivudine] and [adefovir] provides valuable insights into the ongoing quest to conquer this viral infection. Like a desert traveler seeking a life-giving oasis, researchers in the field of [hepatitis B] are continually searching for more effective and durable therapies. The findings of this study offer a promising step forward in this journey, highlighting the potential of [telbivudine] to improve treatment outcomes for patients with [chronic hepatitis B]. This research underscores the importance of ongoing research and innovation in the fight against this debilitating disease.

Date :
  1. Date Completed 2007-12-10
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

17909201

DOI: Digital Object Identifier

10.7326/0003-4819-147-11-200712040-00183

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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