Is topical therapy necessary in acute distal colitis? Double-blind comparison of high-dose oral mesalazine versus steroid enemas in the treatment of active distal ulcerative colitis.

Author: CobdenI, RecordC O, ZaitounA, al-MardiniH

Paper Details 
Original Abstract of the Article :
Thirty-seven patients suffering an attack of acute distal ulcerative colitis of mild or moderate severity were randomized in a double-blind, double-dummy fashion to receive either 800 mg oral mesalazine four times daily (18 patients) or steroid enemas twice daily (19 patients) for 4 weeks. Both trea...See full text at original site
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引用元:
https://doi.org/10.1111/j.1365-2036.1991.tb00520.x

データ提供:米国国立医学図書館(NLM)

Treating Distal Colitis: A Comparative Study

Ulcerative colitis, a chronic inflammatory bowel disease, can cause significant discomfort and impact a patient's daily life. Finding effective and well-tolerated treatments for this condition is a primary concern for healthcare professionals.

This research compares the efficacy of high-dose oral mesalazine versus steroid enemas in treating active distal ulcerative colitis, a form of the disease affecting the lower part of the colon. The study found that both treatments were effective in improving symptoms and reducing inflammation. Imagine two different desert trails leading to a shared oasis – both treatments effectively alleviate the discomfort of distal colitis.

Effective Treatment Options for Ulcerative Colitis

This research highlights the effectiveness of both oral mesalazine and steroid enemas in treating distal ulcerative colitis. The study suggests that choosing the appropriate treatment may depend on individual patient preferences and the severity of their symptoms.

Managing Colitis: Seeking Expert Guidance

This research underscores the importance of seeking expert guidance from a qualified healthcare professional when managing ulcerative colitis. A doctor or other healthcare provider can provide a proper diagnosis, recommend the most appropriate treatment, and monitor progress.

Dr. Camel's Conclusion

This research offers a valuable oasis in the desert of ulcerative colitis treatment, providing insights into the effectiveness of different therapeutic approaches. By working closely with healthcare professionals, patients can navigate this challenging terrain and find the best path toward relief and improved well-being.
Date :
  1. Date Completed 1992-04-08
  2. Date Revised 2019-08-28
Further Info :

Pubmed ID

1793782

DOI: Digital Object Identifier

10.1111/j.1365-2036.1991.tb00520.x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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