A biological approach in a patient with psoriasis and bullous pemphigoid associated with losartan therapy.

Author: ChimentiS, CitarellaL, SaracenoR, SpalloneG

Paper Details 
Original Abstract of the Article :
Several cases of psoriasis associated with bullous disorders have been reported, and it is clearly recognized that bullous pemphigoid (BP) is the most common bullous disorder observed in association with psoriasis, especially after ultraviolet (UV)B and psoralen UVA therapy. Moreover, other medicati...See full text at original site
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引用元:
https://doi.org/10.1111/j.1365-2230.2007.02603.x

データ提供:米国国立医学図書館(NLM)

Psoriasis and Bullous Pemphigoid: A Complex Interplay

This case report investigates the unusual association between psoriasis, a common skin condition, and bullous pemphigoid (BP), a rare autoimmune blistering disorder. The researchers describe a patient with a history of psoriasis who developed BP after initiating treatment with losartan, an angiotensin II receptor antagonist. The study aims to highlight the potential of certain medications to trigger autoimmune diseases and the challenges associated with managing these complex conditions.

Losartan: A Potential Trigger for Autoimmune Disease

The case report suggests that losartan may have played a role in the development of BP in this patient with psoriasis. This finding raises concerns about the potential of angiotensin II receptor antagonists to trigger autoimmune disorders in susceptible individuals. Further research is needed to investigate this potential association and determine the specific risk factors involved.

Navigating the Shifting Sands of Autoimmune Disease

This case report provides a valuable reminder of the complex interplay between medications and autoimmune diseases. The researchers highlight the importance of carefully monitoring patients for potential side effects and considering the possibility of drug-induced autoimmune disorders. A thorough understanding of patient history and medication interactions is crucial for effective management of these complex conditions.

Dr. Camel's Conclusion

This case report, like a hidden oasis in the desert of autoimmune disease, highlights the potential of medications to trigger unexpected complications. The findings serve as a reminder of the importance of vigilance in monitoring patients for potential side effects and considering the possibility of drug-induced autoimmune disorders. By navigating the complexities of autoimmune diseases, healthcare providers can better understand the potential triggers and develop more effective strategies for managing these challenging conditions.

Date :
  1. Date Completed 2008-07-29
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

18021271

DOI: Digital Object Identifier

10.1111/j.1365-2230.2007.02603.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

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