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Adapalene gel 0.1% is effective and safe for Japanese patients with acne vulgaris: a randomized, multicenter, investigator-blinded, controlled study.

Author: HaradaShotaro, KawashimaMakoto, LoescheChristian, MiyachiYoshiki

Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Topical retinoids like adapalene are a key part of acne treatment in many countries and are recommended as the first line treatment for most acne cases, except the most severe. However, topical retinoids are not currently available in Japan for treating acne.
Paper Details　
Original Abstract of the Article :
Topical retinoids, such as adapalene, are an integral part of acne therapy in most regions and are considered appropriate first-line therapy by international guidelines for all cases of acne with the exception of the most severe. However, there are currently no topical retinoids available for the tr...See full text at original site
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引用元：
https://doi.org/10.1016/j.jdermsci.2007.09.012

データ提供：米国国立医学図書館（NLM）

Adapalene Gel: A Safe and Effective Treatment for Acne in Japanese Patients

Acne vulgaris is a common skin condition that can affect individuals of all ages, particularly adolescents. This research evaluates the efficacy and safety of adapalene gel 0.1% for treating acne vulgaris in Japanese patients. The study employed a randomized, multicenter, investigator-blinded, controlled design to compare the effectiveness of adapalene gel to placebo. The study found that adapalene gel was both effective and safe for treating acne in Japanese patients.

Navigating the Desert of Acne Treatment: A New Oasis

The study's findings offer a promising new treatment option for acne vulgaris in Japanese patients, particularly in a region where topical retinoids are not widely available. The study's results suggest that adapalene gel can effectively reduce acne lesions and improve overall skin clarity, offering a new beacon of hope in the desert of acne treatment.

The Importance of Individualized Treatment Approaches

This study highlights the importance of considering individual patient needs and the diversity of skin types when selecting acne treatments. While adapalene gel proved effective in Japanese patients, it's crucial to remember that every individual is unique and may respond differently to treatment. Just as a desert traveler needs to adapt their journey based on the specific terrain, healthcare providers need to individualize treatment plans based on the patient's specific needs and skin characteristics.

Dr. Camel's Conclusion

This research demonstrates the efficacy and safety of adapalene gel 0.1% for treating acne vulgaris in Japanese patients. This study provides a valuable addition to the treatment arsenal for acne, offering a promising solution for individuals seeking effective and safe treatment options. It serves as a reminder that the desert of dermatological research continues to yield new and promising avenues for treating common skin conditions.

Date :
  1. Date Completed 2008-04-08
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

18063345

DOI: Digital Object Identifier

10.1016/j.jdermsci.2007.09.012

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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