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Clinical, functional, and economic ramifications of early nonresponse to antipsychotics in the naturalistic treatment of schizophrenia.

Author: Ascher-SvanumHaya, BakerRobert W, FariesDouglas E, KinonBruce J, NyhuisAllen W, ShekharAnantha

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Early nonresponse to antipsychotics appears to predict subsequent nonresponse to treatment in patients with schizophrenia.
Paper Details　
Original Abstract of the Article :
Early nonresponse to antipsychotics appears to predict subsequent nonresponse to treatment when assessed in randomized controlled trials of predominately acute inpatients treated for schizophrenia. This study assessed the predictive accuracy of early nonresponse to treatment and its clinical, functi...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632496/

データ提供：米国国立医学図書館（NLM）

Early Nonresponse to Antipsychotics: A Warning Sign in the Desert of Schizophrenia

The journey through the desert of schizophrenia can be long and arduous, and identifying early warning signs is crucial for effective treatment. This study explores the predictive power of early nonresponse to antipsychotics, delving into its implications for long-term treatment outcomes. The researchers examined a cohort of predominantly chronic outpatients with schizophrenia, evaluating the predictive accuracy of early nonresponse. The findings suggest that early nonresponse to antipsychotics can serve as a harbinger of subsequent treatment difficulties, highlighting the importance of prompt intervention and personalized treatment strategies.

Navigating the Desert of Schizophrenia: Early Nonresponse as a Guidepost

The research underscores the significance of early nonresponse as a predictor of long-term treatment outcomes in schizophrenia. This information can guide clinicians in tailoring treatment approaches, potentially leading to more effective management strategies and improved outcomes for patients navigating the complexities of schizophrenia. Early intervention can be crucial in this challenging journey.

Early Intervention: A Key to Navigating the Desert of Schizophrenia

The study emphasizes the importance of early intervention in schizophrenia. By recognizing early nonresponse to antipsychotics, clinicians can adjust treatment strategies, potentially improving long-term outcomes. This research highlights the need for individualized care and the importance of close monitoring to ensure that patients receive the most effective treatment possible.

Dr. Camel's Conclusion

Early nonresponse to antipsychotics is like a mirage in the desert: it may seem like a shortcut, but it can actually lead to further challenges. This research emphasizes the importance of recognizing early warning signs and adapting treatment strategies accordingly.

Date :
  1. Date Completed 2009-02-03
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

18156640

DOI: Digital Object Identifier

PMC2632496

Related Literature

Article Analysis
・Effective treatment of schizophrenia
SNS
PICO Info
in preparation
Languages

English

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