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Immunomodulatory effect of gatifloxacin on mouse peritoneal macrophages in vitro and in models of endotoxin-induced rat conjunctivitis and rabbit bacterial keratitis.
Author: InoueTakateru, KidaTetsuo, NakaHiroaki, SakakiHideyuki, TokushigeHideki, WadaTomoyuki
Original Abstract of the Article :
AIM: To determine the anti-inflammatory activity of gatifloxacin in ophthalmic use. METHODS: The following 3 experiments were carried out. (1) Rabbits were inoculated intracorneally with methicillin-resistant Staphylococcus aureus and topically treated with gatifloxacin or levofloxacin. The severit...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1159/000113883
データ提供:米国国立医学図書館(NLM)
Gatifloxacin: A Multifaceted Anti-Inflammatory Agent for Eye Infections
The field of ophthalmology is constantly seeking ways to effectively treat infections and inflammation in the eye. This study investigates the anti-inflammatory properties of gatifloxacin, a fluoroquinolone antibiotic, examining its potential in ophthalmic applications. Imagine the eye as a delicate desert oasis, vulnerable to environmental threats and requiring careful attention.
Gatifloxacin: A Promising Anti-Inflammatory Agent for Ocular Infections
The study reveals that gatifloxacin exhibits both antibacterial and anti-inflammatory activity, effectively reducing ocular inflammation in various models of infection. This suggests that gatifloxacin could be a valuable treatment option for eye infections, offering a multifaceted approach to managing inflammation and infection.
Eye Infections: A Common Concern
Eye infections, like bacterial keratitis and conjunctivitis, can be a significant discomfort. It's crucial to seek prompt medical attention to prevent complications like vision loss. Remember that the desert landscape can harbor many hidden dangers, and it's essential to protect your eyes from potential threats.
Dr.Camel's Conclusion
This research sheds light on the potential of gatifloxacin as a potent anti-inflammatory agent for eye infections. It highlights the importance of investigating the multifaceted properties of medications, especially in delicate areas like the eye. As we continue to explore the vast landscape of ophthalmology, we must strive to find solutions that effectively manage infections and preserve vision.
Date :
- Date Completed 2008-03-27
- Date Revised 2018-12-01
Further Info :
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English
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