Topical glycopyrrolate for patients with facial hyperhidrosis.

Author: KilH K, KimW O, YoonD M, YoonK B

Paper Details 
Original Abstract of the Article :
BACKGROUND: Facial hyperhidrosis may negatively impact the quality of life. Although various conservative modalities have been suggested, the condition is not often treated successfully. OBJECTIVES: To examine whether topical glycopyrrolate could be an effective and safe treatment for facial hyperh...See full text at original site
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引用元:
https://doi.org/10.1111/j.1365-2133.2008.08476.x

データ提供:米国国立医学図書館(NLM)

Topical Glycopyrrolate for Patients with Facial Hyperhidrosis

This research delves into the realm of hyperhidrosis, a condition characterized by excessive sweating. It investigates the effectiveness and safety of topical glycopyrrolate, an anticholinergic medication, in treating facial hyperhidrosis, a particularly bothersome form of this condition.

The study involved 25 patients with facial hyperhidrosis. They received topical glycopyrrolate (2%) on one half of their forehead, while the other half was treated with a placebo. Sweat production rates were carefully measured, and patients reported their level of anhidrosis (absence of sweating) and overall satisfaction with the treatment. The researchers also monitored for any potential side effects.

The results indicated a significant reduction in sweat production on the side of the forehead treated with topical glycopyrrolate compared to the placebo-treated side. The majority of patients (96%) reported being partially or fully satisfied with the treatment's effectiveness in reducing sweating. Although recurrence of sweating was observed in some patients, most experienced relief for at least two days. Only one patient reported a transient headache as a side effect.

Topical Glycopyrrolate as a Potential Treatment for Facial Hyperhidrosis

This research suggests that topical glycopyrrolate could be an effective and safe treatment for facial hyperhidrosis. Its ability to significantly reduce sweat production and improve patient satisfaction makes it a promising option for managing this often-embarrassing condition.

Managing Excessive Sweating

The study highlights the importance of exploring alternative treatment options for hyperhidrosis, particularly for conditions like facial hyperhidrosis, which can significantly impact a person's quality of life. Topical glycopyrrolate offers a non-invasive and potentially effective approach to managing excessive sweating in the facial area.

Dr.Camel's Conclusion

This study demonstrates the effectiveness and safety of topical glycopyrrolate for treating facial hyperhidrosis. The researchers found that this medication significantly reduced sweat production and improved patient satisfaction. While further research is needed to fully understand the long-term effects of topical glycopyrrolate, these findings offer hope for individuals struggling with excessive facial sweating.
Date :
  1. Date Completed 2008-08-27
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

18294315

DOI: Digital Object Identifier

10.1111/j.1365-2133.2008.08476.x

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SNS
PICO Info
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Languages

English

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