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Subtyping panic disorder by major depression and avoidance behaviour and the response to active treatment.

Author: ArgyleN, BenkertO, BrandonS, BullerR, MaierW, RosenbergR, RothM

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

A study investigated the clinical validity of panic disorder subtypes by examining the association of avoidance behavior and depression with treatment response. The study found limited support for the validity of panic disorder subtypes based on avoidance behavior, with patients with agoraphobia responding better to imipramine and those without avoidance responding better to alprazolam.
Paper Details　
Original Abstract of the Article :
In order to establish the clinical validity of currently used ways of subtyping panic disorder the predictive power of associated current avoidance behaviour and (secondary) major depression for the response to active treatment (alprazolam, imipramine) was tested. The analysis was based on the data ...See full text at original site
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引用元：
https://doi.org/10.1007/BF02193750

データ提供：米国国立医学図書館（NLM）

Panic Disorder: A Camel's Journey through Fear and Avoidance

Panic disorder, a debilitating mental health condition, is characterized by intense fear and anxiety, often accompanied by physical symptoms. Imagine a camel in the desert, feeling a sudden surge of panic, fleeing from a perceived threat. This research delves into the complex nature of panic disorder, exploring the role of avoidance behavior and depression in shaping the response to treatment.

Exploring Subtypes of Panic Disorder

The study explores subtypes of panic disorder based on the presence of avoidance behavior and major depression. This is like recognizing different types of camels in a caravan, each with unique characteristics. The researchers investigated how these subtypes influence the effectiveness of treatment with alprazolam and imipramine.

Treatment Response and Subtypes of Panic Disorder

The research found that patients with panic attacks and agoraphobia (intense fear of open spaces) responded better to imipramine than alprazolam. This is like finding that some camels thrive in a specific terrain, while others prefer a different environment. The study highlights the importance of considering individual patient characteristics when selecting the most appropriate treatment.

Dr. Camel's Conclusion

This research offers valuable insights into the different subtypes of panic disorder, reminding us that a one-size-fits-all approach may not be effective. Understanding the interplay of avoidance behavior and depression can help tailor treatment strategies, paving the way for a more successful journey through the desert of panic disorder.

Date :
  1. Date Completed 1991-10-15
  2. Date Revised 2019-10-28
Further Info :

Pubmed ID

1832302

DOI: Digital Object Identifier

10.1007/BF02193750

Related Literature

Article Analysis
・Effective treatment of panic disorder
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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