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Antimicrobial activity of cefditoren tested against contemporary (2004-2006) isolates of Haemophilus influenzae and Moraxella catarrhalis responsible for community-acquired respiratory tract infections in the United States.

Author: BiedenbachDouglas J, FritscheThomas R, JonesRonald N

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Cefditoren, an oral cephalosporin, is a potent agent against Haemophilus influenzae, including beta-lactamase-positive and ampicillin-resistant strains. It is 32 to 512 times more potent than other cephalosporins like cefdinir, cefuroxime, and cefprozil. Cefditoren is also effective against Moraxella catarrhalis, including beta-lactamase producers.
Paper Details　
Original Abstract of the Article :
Among orally administered cephalosporins, aminopenicillins (+/- clavulanate), and macrolides, cefditoren was the most potent agent against Haemophilus influenzae (MIC(50/90), < or =0.008/0.03 microg/mL; 316 isolates including 100 beta-lactamase-positive and 10 beta-lactamase-negative ampicillin-resi...See full text at original site
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引用元：
https://doi.org/10.1016/j.diagmicrobio.2008.01.015

データ提供：米国国立医学図書館（NLM）

Cefditoren: A Potent Weapon Against Respiratory Infections

The world of medicine is constantly battling against the relentless tide of infections. This study focuses on a crucial aspect of this fight: the development of effective antibiotics to combat respiratory infections.

The authors meticulously investigate the efficacy of cefditoren, a cephalosporin antibiotic, against two common culprits of respiratory infections: Haemophilus influenzae and Moraxella catarrhalis. They analyze the minimum inhibitory concentration (MIC), a measure of an antibiotic's potency, for a large collection of these bacteria isolates.

The study reveals that cefditoren exhibits remarkable potency against these bacteria, outperforming other commonly used antibiotics like cefdinir, cefuroxime, and cefprozil. It demonstrates that cefditoren can effectively inhibit the growth of these bacteria, even those with resistance phenotypes, providing a valuable tool for treating respiratory infections.

Cefditoren: A Powerful Antibiotic for Respiratory Infections

The study's findings highlight the remarkable efficacy of cefditoren against Haemophilus influenzae and Moraxella catarrhalis. Its potent activity against these bacteria, even those with resistance phenotypes, underscores its potential as a valuable tool for treating respiratory infections.

A Vital Weapon in the Fight Against Respiratory Infections

This study provides valuable insights into the effectiveness of cefditoren for treating respiratory infections. It's a reminder that ongoing research is crucial for developing new antibiotics to combat the ever-evolving challenges of infectious diseases.

Dr. Camel's Conclusion

Cefditoren emerges as a potent weapon in the fight against respiratory infections. Its effectiveness against a wide range of bacteria, including those with resistance phenotypes, makes it a valuable asset in the medical arsenal.

Date :
  1. Date Completed 2008-07-24
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

18353594

DOI: Digital Object Identifier

10.1016/j.diagmicrobio.2008.01.015

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Languages

English

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