Safety and efficacy of low-dose bexarotene and PUVA in the treatment of patients with mycosis fungoides.

Author: AntoniouChristina, KatsambasAndreas, NikolaouVassiliki, PapadavidEvangelia, SiakantarisMarina, StavrianeasNikolaos, StratigosAlexandros, VassilakopoulosTheodoros P

Paper Details 
Original Abstract of the Article :
The new rexinoid bexarotene is a retinoid X receptor antagonist and immune response modifier. Although combinations of oral bexarotene and psoralen plus UVA (PUVA) have been tried in patients with all stages of mycosis fungoides (MF), the dosage of bexarotene used in these combination regimens has b...See full text at original site
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引用元:
https://doi.org/10.2165/00128071-200809030-00005

データ提供:米国国立医学図書館(NLM)

Exploring New Treatment Strategies for Mycosis Fungoides

The world of dermatology is always searching for effective treatments for skin conditions like mycosis fungoides. This study delves into the potential of combining bexarotene, a retinoid X receptor antagonist, with PUVA (psoralen plus UVA) therapy. This combination therapy aims to tackle mycosis fungoides in all its stages, offering a new approach for this challenging skin disease. The authors investigated various bexarotene dosages within this combination therapy, exploring the optimal balance for achieving positive outcomes.

Tailoring Treatment for Optimal Results

The study highlights the importance of finding the right balance between bexarotene and PUVA to effectively treat mycosis fungoides. This research offers valuable insights for dermatologists seeking to personalize treatment plans for patients with this condition.

Navigating the Desert of Skin Disease

Like a thirsty traveler seeking an oasis in the vast desert, patients with mycosis fungoides yearn for effective treatments. This research offers a potential path toward that oasis, offering hope for those seeking relief from this stubborn skin condition. Remember, as with any medical treatment, careful consideration and a thorough discussion with your dermatologist are essential.

Dr.Camel's Conclusion

This study is like a promising camel caravan venturing into a new territory, searching for a better way to combat mycosis fungoides. The combination of bexarotene and PUVA therapy holds promise for patients seeking a more effective treatment option.

Date :
  1. Date Completed 2008-11-12
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

18429646

DOI: Digital Object Identifier

10.2165/00128071-200809030-00005

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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