Persistence, adherence, and switch rates among extended-release and immediate-release overactive bladder medications in a regional managed care plan.

Author: ArielyRinat, D'SouzaAnna O, DoyleJoseph, MillerLesley-Ann, SmithMichael J

Paper Details 
Original Abstract of the Article :
Pharmacotherapy constitutes an important adjunct to behavioral therapy for the treatment of overactive bladder (OAB). Tolterodine and oxybutynin are commonly prescribed drugs for OAB treatment that exert their beneficial effect by suppressing bladder muscle contractions. However, high discontinuatio...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10438114/

データ提供:米国国立医学図書館(NLM)

Overactive Bladder Medications: A Comparative Study

Overactive bladder (OAB) is a common and often debilitating condition that impacts quality of life. This study explores the effectiveness and persistence of various medications used to manage OAB, focusing on two commonly prescribed drugs: tolterodine and oxybutynin. The researchers sought to compare the persistence and adherence rates of extended-release (ER) formulations to their immediate-release (IR) counterparts.

Navigating the Desert of OAB Treatment: Finding the Right Path

The researchers found that extended-release formulations of tolterodine and oxybutynin were associated with better persistence and adherence compared to their immediate-release counterparts. This finding suggests that extended-release formulations may offer a more manageable approach to OAB treatment, improving patient tolerability and adherence to therapy.

A Journey Through the Desert of OAB: Finding Relief and Managing Side Effects

This study underscores the importance of understanding the individual needs of patients with OAB. While medication can be an effective tool in managing the symptoms of OAB, it's crucial to find the right approach that minimizes side effects and maximizes patient adherence. This research provides valuable insights to guide clinicians in selecting the most appropriate medication and dosage for their patients.

Dr.Camel's Conclusion

This study offers valuable insights into the treatment of OAB, highlighting the importance of finding the right path through the desert of medication options. By considering factors such as patient tolerability, adherence, and medication formulation, healthcare providers can tailor treatment strategies for optimal patient outcomes.

Date :
  1. Date Completed 2008-07-01
  2. Date Revised 2023-08-23
Further Info :

Pubmed ID

18439051

DOI: Digital Object Identifier

PMC10438114

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.