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Clinical trial: asimadoline in the treatment of patients with irritable bowel syndrome.

Author: BornsteinJ D, BudaJ, HammL R, IrishW, MangelA W, UrsoD, WangJ

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Asimaoline showed potential benefit for the treatment of irritable bowel syndrome (IBS).
Paper Details　
Original Abstract of the Article :
BACKGROUND: In models of irritable bowel syndrome (IBS), asimadoline, a kappa-opioid agonist, improves pain and abnormal bowel function. AIM: To evaluate the effects of three doses of asimadoline and placebo in subjects with IBS through a double-blind, randomized, placebo-controlled trial. METHODS...See full text at original site
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引用元：
https://doi.org/10.1111/j.1365-2036.2008.03730.x

データ提供：米国国立医学図書館（NLM）

A New Oasis in the IBS Desert: Exploring Asimadoline

The [irritable bowel syndrome (IBS)] desert is a harsh and unpredictable landscape, with symptoms as elusive as a mirage. This study takes us on a [double-blind, randomized, placebo-controlled trial] to explore the effects of [asimadoline] on [IBS symptoms]. It's like searching for a hidden spring in a seemingly barren wasteland.

A glimmer of hope in the IBS desert

The results suggest that [asimadoline] may offer a promising oasis for [IBS patients], especially those with [diarrhea-predominant IBS] and [moderate pain]. The study found [significant improvement] in [pain relief] and [symptom reduction]. It's like discovering a source of cool water in the midst of the scorching desert.

A New Route Through the IBS Desert

This study suggests that [asimadoline] could be a valuable addition to the [IBS treatment] toolkit. It's like finding a new route through the desert, offering a smoother journey to relief. However, more research is needed to fully understand its potential and to find the best ways to apply it.

Dr.Camel's Conclusion

The search for effective IBS treatment continues, and this research provides a promising lead. It's like a beacon in the night, guiding us toward a better understanding of this challenging condition. As we continue our journey through the IBS desert, it's important to remember that every new discovery is a step closer to finding lasting relief.

Date :
  1. Date Completed 2008-10-13
  2. Date Revised 2022-04-19
Further Info :

Pubmed ID

18466359

DOI: Digital Object Identifier

10.1111/j.1365-2036.2008.03730.x

Related Literature

Article Analysis
・Effective treatment of irritable bowel syndrome
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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