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Effect of doxazosin gastrointestinal therapeutic system as third-line antihypertensive therapy on blood pressure and lipids in the Anglo-Scandinavian Cardiac Outcomes Trial.
Author: , ChangChoon Lan, ChapmanNeil, DahlöfBjörn, PoulterNeil R, SeverPeter S, WedelHans
Original Abstract of the Article :
BACKGROUND: The role of doxazosin in treatment of hypertension remains controversial. METHODS AND RESULTS: We evaluated the effects on blood pressure (BP) and biochemical parameters of doxazosin GITS (gastrointestinal therapeutic system) as a third-line antihypertensive agent among 10,069 participa...See full text at original site
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引用元:
https://doi.org/10.1161/CIRCULATIONAHA.107.737957
データ提供:米国国立医学図書館(NLM)
Doxazosin: A Promising Third-Line Antihypertensive Agent
Hypertension, or high blood pressure, is a prevalent health concern that can significantly increase the risk of heart disease, stroke, and other cardiovascular complications. This research evaluates the efficacy and safety of doxazosin, an alpha-blocker, as a third-line antihypertensive agent. The study analyzed data from the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT-BPLA), a large-scale clinical investigation, to assess the effects of doxazosin on blood pressure and lipid profiles. Researchers found that doxazosin effectively reduced blood pressure and had modest favorable effects on lipid profiles, demonstrating its potential as a third-line antihypertensive agent.
Doxazosin's Effectiveness in Lowering Blood Pressure
The study's findings suggest that doxazosin is an effective third-line antihypertensive agent. The significant reduction in blood pressure observed in the study provides compelling evidence for its efficacy in managing hypertension. It's like discovering a hidden spring in a desert, providing a reliable source of relief for those seeking to lower their blood pressure.
Implications for Hypertension Management
This research highlights the potential of doxazosin as a valuable tool for managing hypertension. The study's findings encourage further investigation into its long-term efficacy and potential for improving cardiovascular health. It's like finding a new path through a desert, leading towards a healthier and more fulfilling life for those living with hypertension.
Dr. Camel's Conclusion
This research provides valuable insights into the efficacy and safety of doxazosin as a third-line antihypertensive agent. The study's findings suggest that doxazosin can effectively lower blood pressure and may offer a viable option for patients who have not achieved adequate control with other medications. It's like discovering a hidden oasis in a desert, offering a potential source of relief for those seeking to manage their hypertension.
Date :
- Date Completed 2008-09-04
- Date Revised 2013-11-21
Further Info :
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