No occurrence of Pneumocystis jiroveci (carinii) pneumonia in 120 adults undergoing myeloablative unrelated cord blood transplantation.

Author: AsanoS, IsekiT, KasaharaS, KatoS, KonumaT, OoiJ, TakahashiS, TojoA, TomonariA, TsukadaN

Paper Details 
Original Abstract of the Article :
The incidence of pneumonia caused by Pneumocystis carinii (PCP) (organism now renamed Pneumocystis jiroveci) during the early period after cord blood transplantation (CBT) was studied in 120 adults. Initially 89 patients (74%) received oral administration of 2 single-strength trimethoprim-sulfametho...See full text at original site
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引用元:
https://doi.org/10.1111/j.1399-3062.2008.00321.x

データ提供:米国国立医学図書館(NLM)

Pneumocystis jiroveci Pneumonia (PCP) in Cord Blood Transplant Recipients: A Desert Oasis of Prevention

This research delves into the complex world of [Cord Blood Transplantation], focusing on the prevention of Pneumocystis jiroveci pneumonia (PCP) in adult recipients. The study investigated the incidence of PCP in 120 adults undergoing myeloablative unrelated cord blood transplantation (CBT). The researchers found that none of the 120 patients developed PCP within 100 days or 2 years after CBT, suggesting that PCP during the early period after CBT can be effectively prevented by pre-transplant prophylactic methods. Interestingly, one patient who received prophylaxis before but not after CBT developed cerebral toxoplasmosis, highlighting the importance of continued prophylaxis after transplantation.

Prophylactic Methods: A Shield Against PCP

This study provides compelling evidence that pre-transplant prophylaxis effectively prevents PCP in adult cord blood transplant recipients. This is akin to providing a camel with a sturdy tent to protect it from the harsh desert elements. These findings are encouraging for patients undergoing CBT, as they indicate that with appropriate preventive measures, the risk of PCP can be significantly reduced.

Cord Blood Transplantation: Safeguarding Patient Health

This research underlines the importance of meticulous prevention strategies for patients undergoing cord blood transplantation. It highlights the critical role of proactive healthcare in safeguarding patient health and ensuring a successful transplant experience. Just as a desert explorer relies on a reliable compass for safe navigation, patients undergoing CBT need comprehensive preventive measures to navigate the potential risks and complications of the procedure.

Dr.Camel's Conclusion

This research is a testament to the power of prevention in healthcare. The study demonstrates that pre-transplant prophylactic methods effectively prevent PCP in adult cord blood transplant recipients, offering a significant advantage for these patients. Just as a desert oasis provides a safe haven from the harsh conditions, pre-transplant prophylaxis safeguards patients from the threat of PCP, enabling them to thrive in the post-transplant period.

Date :
  1. Date Completed 2008-12-15
  2. Date Revised 2020-12-09
Further Info :

Pubmed ID

18564982

DOI: Digital Object Identifier

10.1111/j.1399-3062.2008.00321.x

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SNS
PICO Info
in preparation
Languages

English

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