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Cervical cancer vaccination indications, efficacy, and side effects.

Author: BayasJosé-María, CostasLaura, MuñozAmparo

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Human papillomavirus (HPV) vaccines (Gardasil and Cervarix) offer protection against persistent HPV infection and associated diseases, such as cervical cancer. These vaccines use L1 capsular proteins for genotypes 16 and 18, responsible for 70% of uterine cancers worldwide. Phase I-III trials demonstrated the vaccines' safety, high antibody titers, and efficacy in preventing infection and cervical intraepithelial neoplasia (CIN) associated with vaccine genotypes. The optimal strategy is vaccination of girls aged 8-14 years, with catch-up vaccination for adolescents and women. Successful implementation requires public health support, coordination of healthcare workers, and increased public awareness.
Paper Details　
Original Abstract of the Article :
Due to the limited contact of the human papillomavirus (HPV) with the immune system, past infection does not guarantee lasting protection. Two preventive vaccines (Gardasil and Cervarix) that can impede persistent HPV infection and its consequences are now available. They use structural L1 capsular ...See full text at original site
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引用元：
https://doi.org/10.1016/j.ygyno.2008.05.011

データ提供：米国国立医学図書館（NLM）

Cervical Cancer Vaccines: A Breakthrough in Prevention

Cervical cancer is a serious threat to women's health, and finding effective ways to prevent it is a priority. This research explores the development and efficacy of two preventive HPV vaccines, Gardasil and Cervarix. It's like finding a new way to navigate the treacherous desert of cervical cancer, offering a more effective way to prevent this disease.

The researchers used [research methods] to assess the safety and efficacy of these vaccines in preventing HPV infection and cervical intraepithelial neoplasia (CIN). Their findings indicate that these vaccines are highly effective in preventing persistent HPV infection and its associated health risks.

A New Oasis in the Desert of Cervical Cancer

The study suggests that HPV vaccines, like a newly discovered oasis, offer a promising solution to the challenge of cervical cancer prevention. These vaccines have the potential to significantly reduce the incidence of this disease and its associated health risks.

Navigating the Desert of Cervical Cancer Prevention

This research underscores the importance of vaccination as a key strategy in cervical cancer prevention. It's like having a reliable compass to guide us through the complex desert landscape of cervical cancer prevention. By understanding the risks and benefits of vaccination, we can make informed decisions about our health and the health of our communities.

Dr.Camel's Conclusion

This research highlights the significant potential of HPV vaccines to prevent cervical cancer. It's a testament to the power of science to find innovative solutions for challenging health problems. Like a traveler discovering a new path through a desert, these vaccines offer hope for a healthier future.

Date :
  1. Date Completed 2008-09-24
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

18586311

DOI: Digital Object Identifier

10.1016/j.ygyno.2008.05.011

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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