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Pharmacokinetics of lidocaine following the application of 5% lidocaine patches to cats.

Author: AbboL A, KoJ C H, MaxwellL K, WeilA B

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Lidocaine patches provide local analgesia in cats, with low systemic absorption and high local concentrations. The study found that only a small portion of the lidocaine dose reaches systemic circulation, while high concentrations remain in the skin, supporting the safe use of lidocaine patches in cats.
Paper Details　
Original Abstract of the Article :
Lidocaine patches have been used to provide local analgesia in dogs and cats. We conducted this study to assess the systemic and local absorption of lidocaine from topical patches in cats. Eight 2-year-old cats received either intravenous lidocaine at 2 mg/kg or one 700 mg lidocaine patch placed on ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1111/j.1365-2885.2008.00967.x

データ提供：米国国立医学図書館（NLM）

A Study on the Systemic and Local Absorption of Lidocaine in Cats

The world of veterinary medicine is a fascinating desert, full of unique challenges. This study explores the pharmacokinetics of lidocaine, a common local anesthetic, in cats. The authors investigated the systemic and local absorption of lidocaine from topical patches, shedding light on the effectiveness and safety of this treatment method in feline patients.

Lidocaine Patches: A Safe and Effective Option for Cats

The study found that lidocaine patches provided effective local analgesia in cats, achieving high concentrations of lidocaine in the skin while maintaining low systemic levels, ensuring safety for the animal. The authors emphasize the importance of this finding, as it suggests that lidocaine patches can be a safe and effective option for providing pain relief to cats.

Understanding Drug Absorption and Metabolism

The study also provides valuable insights into the pharmacokinetics of lidocaine in cats, highlighting the importance of understanding drug absorption and metabolism in different species. This knowledge is crucial for ensuring appropriate drug dosage and minimizing the risk of adverse effects, protecting the health and well-being of our furry friends.

Dr. Camel's Conclusion

This study sheds light on the nuances of drug delivery and absorption in our feline companions. As we venture through the desert of veterinary medicine, it is essential to approach each case with a thorough understanding of the unique characteristics of our patients. By understanding how drugs work within their bodies, we can ensure the safety and well-being of our feline friends.

Date :
  1. Date Completed 2008-09-09
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

18638297

DOI: Digital Object Identifier

10.1111/j.1365-2885.2008.00967.x

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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